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First episode psychosis (FEP) constitutes an important subgroup within psychotic disorders, as the acute impact of a disorder at the time of diagnosis may differ from its long-term impact over the following decades. Narrative is identified as a sense of personal agency, of belonging to a social group, metacognition, and well-being. Patients with schizophrenia have lower levels of agency and communion compared to HIV-positive participants. However, the themes of agency and communion and metacognition do not reflect all factors representing narrative identity. In order to measure well-being, it is also necessary to introduce a specific and multidimensional measure that will allow a more precise understanding of the phenomenon.
In FEP, a link has been demonstrated between the specificity of self-recollection and functional outcomes. Given that the transitional developmental stage between adolescence and adulthood is a key developmental window for narrative identity as well as psychotic disorders and that narrative identity is positively associated with mental health, this study will therefore focus on the acquisition of narrative identity in the FEP. It will investigate the extent to which narrative identity has an impact on multidimensional subjective well-being and whether it can predict multidimensional subjective well-being over time. The study investigators hypothesize that the levels of the various components of narrative identity would be lower in cases of FEP compared to patients with other "chronic" psychotic conditions and controls.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| First episode psychosis |
| ||
| Chronic | participants diagnosed with a psychotic disorder |
| |
| Control |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Narrative identity task | Other | Participants will be asked to elaborate five personal narratives in response to the different types of questions: trauma, transgression, negative memory, self-definition, and turning point. |
| Measure | Description | Time Frame |
|---|---|---|
| Emotional valence according to the question: "When you think about this story in your life, how positive or negative is this story in your life?" | 7-point scale ranging from -3 "Extremely negative" to 3 "Extremely positive" | Baseline (Day 0) |
| Emotional valence according to the question: "When you think about this story in your life, how positive or negative is this story in your life?" | 7-point scale ranging from -3 "Extremely negative" to 3 "Extremely positive" | Month 6 |
| Emotional valence according to the question: "When you think about this story in your life, how positive or negative is this story in your life?" | 7-point scale ranging from -3 "Extremely negative" to 3 "Extremely positive" | Month 12 |
| Emotional valence according to the question: "When you think about this story in your life, how positive or negative is this story in your life?" | 7-point scale ranging from -3 "Extremely negative" to 3 "Extremely positive" | Month 18 |
| Emotional valence according to the question: "When you think about this story in your life, how positive or negative is this story in your life?" | 7-point scale ranging from -3 "Extremely negative" to 3 "Extremely positive" | Month 24 |
| Emotional intensity according to the question: "When you think about this story in your life, how intense is this story in your life?" | 7-point scale ranging from 1 "Not at all intense" to 7 "Extremely intense" - | Baseline (Day 0) |
| Measure | Description | Time Frame |
|---|---|---|
| Narrative identity between groups | PERMA Profiler questionnaire; a 15-item scale in which higher scores indicate greater well-being | Baseline (Day 0) |
| Narrative identity between groups | PERMA Profiler questionnaire; a 15-item scale in which higher scores indicate greater well-being |
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Inclusion Criteria:
For the FEP group:
For the "Chronic" group:
• Patients diagnosed with a disorder meeting DSM-5 criteria for more than 18 months from the following list: delusional disorder, brief psychotic disorder lasting more than 7 days, schizophreniform disorder, schizophrenia, schizoaffective disorder, substance-induced psychotic disorder lasting more than 7 days, other specific or non-specific schizophrenia spectrum disorder or other psychotic disorder, bipolar I or II disorder with mood-congruent and mood-incongruent psychotic features, substance-induced bipolar disorder with mood-congruent and mood-incongruent psychotic features, major depressive disorder with mood-congruent and mood-incongruent psychotic features
Exclusion Criteria:
For the FEP group:
• FEP related to a drug-induced psychotic disorder or due to another medical condition
For the "Control" group:
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406 / 5,000
Three groups of participants will be formed:
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Julie Jourdan | Contact | 04.66.68.34.26 | julie.jourdan@chu-nimes.fr |
| Name | Affiliation | Role |
|---|---|---|
| Julie Jourdan | Centre Hospitalier Universitaire de Nīmes | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU de Nîmes | Nîmes | 30029 | France |
|
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| Emotional intensity according to the question: "When you think about this story in your life, how intense is this story in your life?" | 7-point scale ranging from 1 "Not at all intense" to 7 "Extremely intense" - | Month 6 |
| Emotional intensity according to the question: "When you think about this story in your life, how intense is this story in your life?" | 7-point scale ranging from 1 "Not at all intense" to 7 "Extremely intense" - | Month 12 |
| Emotional intensity according to the question: "When you think about this story in your life, how intense is this story in your life?" | 7-point scale ranging from 1 "Not at all intense" to 7 "Extremely intense" - | Month 18 |
| Emotional intensity according to the question: "When you think about this story in your life, how intense is this story in your life?" | 7-point scale ranging from 1 "Not at all intense" to 7 "Extremely intense" - | Month 24 |
| Emotional tone according to the question "When you think about this story in your life, is it generally negative, mixed, neutral, or positive?" | 4-point scale ranging from 0 "Negative" to 4 "Positive." | Baseline (day 0) |
| Emotional tone according to the question "When you think about this story in your life, is it generally negative, mixed, neutral, or positive?" | 4-point scale ranging from 0 "Negative" to 4 "Positive." | Month 6 |
| Emotional tone according to the question "When you think about this story in your life, is it generally negative, mixed, neutral, or positive?" | 4-point scale ranging from 0 "Negative" to 4 "Positive." | Month 12 |
| Emotional tone according to the question "When you think about this story in your life, is it generally negative, mixed, neutral, or positive?" | 4-point scale ranging from 0 "Negative" to 4 "Positive." | Month 18 |
| Emotional tone according to the question "When you think about this story in your life, is it generally negative, mixed, neutral, or positive?" | 4-point scale ranging from 0 "Negative" to 4 "Positive." | Month 24 |
| Month 6 |
| Narrative identity between groups | PERMA Profiler questionnaire; a 15-item scale in which higher scores indicate greater well-being | Month 12 |
| Narrative identity between groups | PERMA Profiler questionnaire; a 15-item scale in which higher scores indicate greater well-being | Month 18 |
| Narrative identity between groups | PERMA Profiler questionnaire; a 15-item scale in which higher scores indicate greater well-being | Month 24 |
| General health-related quality of life between groups | EQ5D-5L questionnaire comprising five items representing the five dimensions, and a visual analog scale ranging from 0 to 100 (100 referring to the "best possible health state"). The responses are then into a 5-digit number describing the patient's health state (e.g "11111" indicates the absence of problems). | Baseline (day 0) |
| General health-related quality of life between groups | EQ5D-5L questionnaire comprising five items representing the five dimensions, and a visual analog scale ranging from 0 to 100 (100 referring to the "best possible health state"). The responses are then into a 5-digit number describing the patient's health state (e.g "11111" indicates the absence of problems). | Month 6 |
| General health-related quality of life between groups | EQ5D-5L questionnaire comprising five items representing the five dimensions, and a visual analog scale ranging from 0 to 100 (100 referring to the "best possible health state"). The responses are then into a 5-digit number describing the patient's health state (e.g "11111" indicates the absence of problems). | Month 12 |
| General health-related quality of life between groups | EQ5D-5L questionnaire comprising five items representing the five dimensions, and a visual analog scale ranging from 0 to 100 (100 referring to the "best possible health state"). The responses are then into a 5-digit number describing the patient's health state (e.g "11111" indicates the absence of problems). | Month 18 |
| General health-related quality of life between groups | EQ5D-5L questionnaire comprising five items representing the five dimensions, and a visual analog scale ranging from 0 to 100 (100 referring to the "best possible health state"). The responses are then into a 5-digit number describing the patient's health state (e.g "11111" indicates the absence of problems). | Month 24 |
| Health-related quality of life between groups | WHOQOL-Brief: a 26-item questionnaire including one item on overall quality of life, one item assessing general health, and one item from each of the 24 facets of the WHOQOL-100. Four types of five-point response scales measure intensity (Not at all-Extremely), capacity (Not at all-Completely), frequency (Never-Always), and evaluation (Very dissatisfied/Very poor-Very satisfied/Very good). | Baseline (day 0) |
| Health-related quality of life between groups | WHOQOL-Brief: a 26-item questionnaire including one item on overall quality of life, one item assessing general health, and one item from each of the 24 facets of the WHOQOL-100. Four types of five-point response scales measure intensity (Not at all-Extremely), capacity (Not at all-Completely), frequency (Never-Always), and evaluation (Very dissatisfied/Very poor-Very satisfied/Very good). | Month 6 |
| Health-related quality of life between groups | WHOQOL-Brief: a 26-item questionnaire including one item on overall quality of life, one item assessing general health, and one item from each of the 24 facets of the WHOQOL-100. Four types of five-point response scales measure intensity (Not at all-Extremely), capacity (Not at all-Completely), frequency (Never-Always), and evaluation (Very dissatisfied/Very poor-Very satisfied/Very good). | Month 12 |
| Health-related quality of life between groups | WHOQOL-Brief: a 26-item questionnaire including one item on overall quality of life, one item assessing general health, and one item from each of the 24 facets of the WHOQOL-100. Four types of five-point response scales measure intensity (Not at all-Extremely), capacity (Not at all-Completely), frequency (Never-Always), and evaluation (Very dissatisfied/Very poor-Very satisfied/Very good). | Month 18 |
| Health-related quality of life between groups | WHOQOL-Brief: a 26-item questionnaire including one item on overall quality of life, one item assessing general health, and one item from each of the 24 facets of the WHOQOL-100. Four types of five-point response scales measure intensity (Not at all-Extremely), capacity (Not at all-Completely), frequency (Never-Always), and evaluation (Very dissatisfied/Very poor-Very satisfied/Very good). | Month 24 |
| Anxiety and depression between groups | Hospital Anxiety and Depression Scale questionnaire where a higher score indicates greater distress | Baseline (Day 0) |
| Anxiety and depression between groups | Hospital Anxiety and Depression Scale questionnaire where a higher score indicates greater distress | Month 6 |
| Anxiety and depression between groups | Hospital Anxiety and Depression Scale questionnaire where a higher score indicates greater distress | Month 12 |
| Anxiety and depression between groups | Hospital Anxiety and Depression Scale questionnaire where a higher score indicates greater distress | Month 18 |
| Anxiety and depression between groups | Hospital Anxiety and Depression Scale questionnaire where a higher score indicates greater distress | Month 24 |
| Autobiographical memory between groups | Thinking About Life Experiences scale (TALE-15): 17-item questionnaire consists of two general questions followed by 15 specific items related to the functions of autobiographical memory, each composed of 5 sub-items. Responses are rated on a 5-point Likert scale ranging from "Almost never" to "Very frequently." | Baseline (day 0) |
| Autobiographical memory between groups | Thinking About Life Experiences scale (TALE-15): 17-item questionnaire consists of two general questions followed by 15 specific items related to the functions of autobiographical memory, each composed of 5 sub-items. Responses are rated on a 5-point Likert scale ranging from "Almost never" to "Very frequently." | Month 6 |
| Autobiographical memory between groups | Thinking About Life Experiences scale (TALE-15): 17-item questionnaire consists of two general questions followed by 15 specific items related to the functions of autobiographical memory, each composed of 5 sub-items. Responses are rated on a 5-point Likert scale ranging from "Almost never" to "Very frequently." | Month 12 |
| Autobiographical memory between groups | Thinking About Life Experiences scale (TALE-15): 17-item questionnaire consists of two general questions followed by 15 specific items related to the functions of autobiographical memory, each composed of 5 sub-items. Responses are rated on a 5-point Likert scale ranging from "Almost never" to "Very frequently." | Month 18 |
| Autobiographical memory between groups | Thinking About Life Experiences scale (TALE-15): 17-item questionnaire consists of two general questions followed by 15 specific items related to the functions of autobiographical memory, each composed of 5 sub-items. Responses are rated on a 5-point Likert scale ranging from "Almost never" to "Very frequently." | Month 24 |
| Personality type between groups | Big Five Inventory (BFI-10): assessing the five major personality traits: extraversion, agreeableness, conscientiousness, emotional stability, and openness. | Baseline (day 0) |
| Personality type between groups | Big Five Inventory (BFI-10): assessing the five major personality traits: extraversion, agreeableness, conscientiousness, emotional stability, and openness. | Month 6 |
| Personality type between groups | Big Five Inventory (BFI-10): assessing the five major personality traits: extraversion, agreeableness, conscientiousness, emotional stability, and openness. | Month 12 |
| Personality type between groups | Big Five Inventory (BFI-10): assessing the five major personality traits: extraversion, agreeableness, conscientiousness, emotional stability, and openness. | Month 18 |
| Personality type between groups | Big Five Inventory (BFI-10): assessing the five major personality traits: extraversion, agreeableness, conscientiousness, emotional stability, and openness. | Month 24 |
| Symptomatology of psychotic disorders in the FEP and chronic groups | Positive and negative symptom scale (PANSS). 30 items measuring 5 subscales: positive, negative, disorganization, hostility, and anxiety. Each item is rated on a 7-point Likert scale ranging from 1 (absent) to 7 (extreme). The positive subscale ranges from 7 to 49, the negative subscale from 8 to 56, the hostility subscale from 6 to 46, the disorganization subscale from 5 to 35, and the anxiety subscale from 4 to 28. The total score ranges from 30 to 210. | Baseline (day 0) |
| Symptomatology of psychotic disorders in the FEP and chronic groups | Positive and negative symptom scale (PANSS). 30 items measuring 5 subscales: positive, negative, disorganization, hostility, and anxiety. Each item is rated on a 7-point Likert scale ranging from 1 (absent) to 7 (extreme). The positive subscale ranges from 7 to 49, the negative subscale from 8 to 56, the hostility subscale from 6 to 46, the disorganization subscale from 5 to 35, and the anxiety subscale from 4 to 28. The total score ranges from 30 to 210. | Month 6 |
| Symptomatology of psychotic disorders in the FEP and chronic groups | Positive and negative symptom scale (PANSS). 30 items measuring 5 subscales: positive, negative, disorganization, hostility, and anxiety. Each item is rated on a 7-point Likert scale ranging from 1 (absent) to 7 (extreme). The positive subscale ranges from 7 to 49, the negative subscale from 8 to 56, the hostility subscale from 6 to 46, the disorganization subscale from 5 to 35, and the anxiety subscale from 4 to 28. The total score ranges from 30 to 210. | Month 12 |
| Symptomatology of psychotic disorders in the FEP and chronic groups | Positive and negative symptom scale (PANSS). 30 items measuring 5 subscales: positive, negative, disorganization, hostility, and anxiety. Each item is rated on a 7-point Likert scale ranging from 1 (absent) to 7 (extreme). The positive subscale ranges from 7 to 49, the negative subscale from 8 to 56, the hostility subscale from 6 to 46, the disorganization subscale from 5 to 35, and the anxiety subscale from 4 to 28. The total score ranges from 30 to 210. | Month 18 |
| Symptomatology of psychotic disorders in the FEP and chronic groups | Positive and negative symptom scale (PANSS). 30 items measuring 5 subscales: positive, negative, disorganization, hostility, and anxiety. Each item is rated on a 7-point Likert scale ranging from 1 (absent) to 7 (extreme). The positive subscale ranges from 7 to 49, the negative subscale from 8 to 56, the hostility subscale from 6 to 46, the disorganization subscale from 5 to 35, and the anxiety subscale from 4 to 28. The total score ranges from 30 to 210. | Month 24 |
| Overall functioning in the FEP and chronic groups | Global Assessment of Functioning (GAF). This numerical scale (from 0 to 100) subjectively assesses functioning in social, occupational, and psychological domains. Lower scores represent lower levels of functioning | Baseline (day 0) |
| Overall functioning in the FEP and chronic groups | Global Assessment of Functioning (GAF). This numerical scale (from 0 to 100) subjectively assesses functioning in social, occupational, and psychological domains. Lower scores represent lower levels of functioning | Month 6 |
| Overall functioning in the FEP and chronic groups | Global Assessment of Functioning (GAF). This numerical scale (from 0 to 100) subjectively assesses functioning in social, occupational, and psychological domains. Lower scores represent lower levels of functioning | Month 12 |
| Overall functioning in the FEP and chronic groups | Global Assessment of Functioning (GAF). This numerical scale (from 0 to 100) subjectively assesses functioning in social, occupational, and psychological domains. Lower scores represent lower levels of functioning | Month 18 |
| Overall functioning in the FEP and chronic groups | Global Assessment of Functioning (GAF). This numerical scale (from 0 to 100) subjectively assesses functioning in social, occupational, and psychological domains. Lower scores represent lower levels of functioning | Month 24 |
| Personal recovery in the FEP and chronic groups | Stage of recovery instrument (STORI): a 50-item questionnaire that evaluates the five stages of personal recovery. Ten themes are assessed, each containing five items ranging from 0 "Not at all true" to 5 "Completely true," corresponding to the five stages of personal recovery. A score is calculated for each stage, ranging from 0 to 50 | Baseline (day 0) |
| Personal recovery in the FEP and chronic groups | Stage of recovery instrument (STORI): a 50-item questionnaire that evaluates the five stages of personal recovery. Ten themes are assessed, each containing five items ranging from 0 "Not at all true" to 5 "Completely true," corresponding to the five stages of personal recovery. A score is calculated for each stage, ranging from 0 to 50 | Month 6 |
| Personal recovery in the FEP and chronic groups | Stage of recovery instrument (STORI): a 50-item questionnaire that evaluates the five stages of personal recovery. Ten themes are assessed, each containing five items ranging from 0 "Not at all true" to 5 "Completely true," corresponding to the five stages of personal recovery. A score is calculated for each stage, ranging from 0 to 50 | Month 12 |
| Personal recovery in the FEP and chronic groups | Stage of recovery instrument (STORI): a 50-item questionnaire that evaluates the five stages of personal recovery. Ten themes are assessed, each containing five items ranging from 0 "Not at all true" to 5 "Completely true," corresponding to the five stages of personal recovery. A score is calculated for each stage, ranging from 0 to 50 | Month 18 |
| Personal recovery in the FEP and chronic groups | Stage of recovery instrument (STORI): a 50-item questionnaire that evaluates the five stages of personal recovery. Ten themes are assessed, each containing five items ranging from 0 "Not at all true" to 5 "Completely true," corresponding to the five stages of personal recovery. A score is calculated for each stage, ranging from 0 to 50 | Month 24 |
| Social and individual performance in the FEP and chronic groups | Personal and social performance scale (PSP): measures four domains of social and individual functioning (socially useful activities, personal and social relationships, self-care, disruptive and aggressive behaviors) and provides a score between 1 and 100, divided into 10 equal intervals to assess the degree of difficulty. Higher scores correspond to better personal and social functioning, with scores of 91 to 100 indicating more than adequate functioning, while scores below 30 indicate such poor functioning that intensive supervision is required. | Baseline (day 0) |
| Social and individual performance in the FEP and chronic groups | Personal and social performance scale (PSP): measures four domains of social and individual functioning (socially useful activities, personal and social relationships, self-care, disruptive and aggressive behaviors) and provides a score between 1 and 100, divided into 10 equal intervals to assess the degree of difficulty. Higher scores correspond to better personal and social functioning, with scores of 91 to 100 indicating more than adequate functioning, while scores below 30 indicate such poor functioning that intensive supervision is required. | Month 6 |
| Social and individual performance in the FEP and chronic groups | Personal and social performance scale (PSP): measures four domains of social and individual functioning (socially useful activities, personal and social relationships, self-care, disruptive and aggressive behaviors) and provides a score between 1 and 100, divided into 10 equal intervals to assess the degree of difficulty. Higher scores correspond to better personal and social functioning, with scores of 91 to 100 indicating more than adequate functioning, while scores below 30 indicate such poor functioning that intensive supervision is required. | Month 12 |
| Social and individual performance in the FEP and chronic groups | Personal and social performance scale (PSP): measures four domains of social and individual functioning (socially useful activities, personal and social relationships, self-care, disruptive and aggressive behaviors) and provides a score between 1 and 100, divided into 10 equal intervals to assess the degree of difficulty. Higher scores correspond to better personal and social functioning, with scores of 91 to 100 indicating more than adequate functioning, while scores below 30 indicate such poor functioning that intensive supervision is required. | Month 18 |
| Social and individual performance in the FEP and chronic groups | Personal and social performance scale (PSP): measures four domains of social and individual functioning (socially useful activities, personal and social relationships, self-care, disruptive and aggressive behaviors) and provides a score between 1 and 100, divided into 10 equal intervals to assess the degree of difficulty. Higher scores correspond to better personal and social functioning, with scores of 91 to 100 indicating more than adequate functioning, while scores below 30 indicate such poor functioning that intensive supervision is required. | Month 24 |
| Improvement of clinical state in the FEP and chronic groups | Clinical global impression (CGI): a global observer-rated assessment tool that measures a patient's clinical condition before and after medical treatment. It consists of two measures: Severity, which measures the severity of the patient's clinical condition; and Improvement, which assesses the improvement in the patient's clinical condition since the start of treatment, both on a scale of 1 to 7. | Baseline (day 0) |
| Improvement of clinical state in the FEP and chronic groups | Clinical global impression (CGI): a global observer-rated assessment tool that measures a patient's clinical condition before and after medical treatment. It consists of two measures: Severity, which measures the severity of the patient's clinical condition; and Improvement, which assesses the improvement in the patient's clinical condition since the start of treatment, both on a scale of 1 to 7. | Month 6 |
| Improvement of clinical state in the FEP and chronic groups | Clinical global impression (CGI): a global observer-rated assessment tool that measures a patient's clinical condition before and after medical treatment. It consists of two measures: Severity, which measures the severity of the patient's clinical condition; and Improvement, which assesses the improvement in the patient's clinical condition since the start of treatment, both on a scale of 1 to 7. | Month 12 |
| Improvement of clinical state in the FEP and chronic groups | Clinical global impression (CGI): a global observer-rated assessment tool that measures a patient's clinical condition before and after medical treatment. It consists of two measures: Severity, which measures the severity of the patient's clinical condition; and Improvement, which assesses the improvement in the patient's clinical condition since the start of treatment, both on a scale of 1 to 7. | Month 18 |
| Improvement of clinical state in the FEP and chronic groups | Clinical global impression (CGI): a global observer-rated assessment tool that measures a patient's clinical condition before and after medical treatment. It consists of two measures: Severity, which measures the severity of the patient's clinical condition; and Improvement, which assesses the improvement in the patient's clinical condition since the start of treatment, both on a scale of 1 to 7. | Month 24 |
| Awareness of the disorders in the FEP and chronic groups | Birchwood insight scale (BIS); multidimensional assessment of awareness of illness (insight) and includes 8 questions (3-point Likert scale: "agree," "disagree," or "uncertain"). The overall score ranges from 0 to 12, with a score above 9 indicating good insight. | Baseline (day 0) |
| Awareness of the disorders in the FEP and chronic groups | Birchwood insight scale (BIS); multidimensional assessment of awareness of illness (insight) and includes 8 questions (3-point Likert scale: "agree," "disagree," or "uncertain"). The overall score ranges from 0 to 12, with a score above 9 indicating good insight. | Month 6 |
| Awareness of the disorders in the FEP and chronic groups | Birchwood insight scale (BIS); multidimensional assessment of awareness of illness (insight) and includes 8 questions (3-point Likert scale: "agree," "disagree," or "uncertain"). The overall score ranges from 0 to 12, with a score above 9 indicating good insight. | Month 12 |
| Awareness of the disorders in the FEP and chronic groups | Birchwood insight scale (BIS); multidimensional assessment of awareness of illness (insight) and includes 8 questions (3-point Likert scale: "agree," "disagree," or "uncertain"). The overall score ranges from 0 to 12, with a score above 9 indicating good insight. | Month 18 |
| Awareness of the disorders in the FEP and chronic groups | Birchwood insight scale (BIS); multidimensional assessment of awareness of illness (insight) and includes 8 questions (3-point Likert scale: "agree," "disagree," or "uncertain"). The overall score ranges from 0 to 12, with a score above 9 indicating good insight. | Month 24 |
| Abstract verbal reasoning in the FEP and chronic groups | Similarities section of the Wechsler Adult Intelligence Scale (WAIS): For 18 pairs of words, the participant subject must identify the qualitative relationship between the two words | Baseline (day 0) |
| Abstract verbal reasoning in the FEP and chronic groups | Similarities section of the Wechsler Adult Intelligence Scale (WAIS): For 18 pairs of words, the participant subject must identify the qualitative relationship between the two words | Month 6 |
| Abstract verbal reasoning in the FEP and chronic groups | Similarities section of the Wechsler Adult Intelligence Scale (WAIS): For 18 pairs of words, the participant subject must identify the qualitative relationship between the two words | Month 12 |
| Abstract verbal reasoning in the FEP and chronic groups | Similarities section of the Wechsler Adult Intelligence Scale (WAIS): For 18 pairs of words, the participant subject must identify the qualitative relationship between the two words | Month 18 |
| Abstract verbal reasoning in the FEP and chronic groups | Similarities section of the Wechsler Adult Intelligence Scale (WAIS): For 18 pairs of words, the participant subject must identify the qualitative relationship between the two words | Month 24 |
| Non-verbal abstract problem solving in the FEP and chronic groups | Matrix reasoning section of the Wechsler Adult Intelligence Scale (WAIS); in which participants must identify patterns in drawings | Baseline (day 0) |
| Non-verbal abstract problem solving in the FEP and chronic groups | Matrix reasoning section of the Wechsler Adult Intelligence Scale (WAIS); in which participants must identify patterns in drawings | Month 6 |
| Non-verbal abstract problem solving in the FEP and chronic groups | Matrix reasoning section of the Wechsler Adult Intelligence Scale (WAIS); in which participants must identify patterns in drawings | Month 12 |
| Non-verbal abstract problem solving in the FEP and chronic groups | Matrix reasoning section of the Wechsler Adult Intelligence Scale (WAIS); in which participants must identify patterns in drawings | Month 18 |
| Non-verbal abstract problem solving in the FEP and chronic groups | Matrix reasoning section of the Wechsler Adult Intelligence Scale (WAIS); in which participants must identify patterns in drawings | Month 24 |
| Treatment adherence in the FEP and chronic groups | Medication adherence rating scale (MARS): 10-item questionnaire concerning medication adherence during the past week assessing behaviors, attitudes, and experiences related to the treatment. | Baseline (day 0) |
| Treatment adherence in the FEP and chronic groups | Medication adherence rating scale (MARS): 10-item questionnaire concerning medication adherence during the past week assessing behaviors, attitudes, and experiences related to the treatment. | Month 6 |
| Treatment adherence in the FEP and chronic groups | Medication adherence rating scale (MARS): 10-item questionnaire concerning medication adherence during the past week assessing behaviors, attitudes, and experiences related to the treatment. | Month 12 |
| Treatment adherence in the FEP and chronic groups | Medication adherence rating scale (MARS): 10-item questionnaire concerning medication adherence during the past week assessing behaviors, attitudes, and experiences related to the treatment. | Month 18 |
| Treatment adherence in the FEP and chronic groups | Medication adherence rating scale (MARS): 10-item questionnaire concerning medication adherence during the past week assessing behaviors, attitudes, and experiences related to the treatment. | Month 24 |
| Episodic memory between groups | California Verbal Learning Test--Second Edition (CVLT): in this word list recall and recognition test, the examiner reads a list of 16 nouns aloud at one-second intervals in a fixed order over five learning trials. The participant is asked to recall as many words as possible in any order (free recall). If subjects "cluster" words from each category, they are presumably using semantic organization. Free recall is tested immediately (short-term recall) and again after 20 minutes (long-term recall). | Baseline (day 0) |
| Episodic memory between groups | California Verbal Learning Test--Second Edition (CVLT): in this word list recall and recognition test, the examiner reads a list of 16 nouns aloud at one-second intervals in a fixed order over five learning trials. The participant is asked to recall as many words as possible in any order (free recall). If subjects "cluster" words from each category, they are presumably using semantic organization. Free recall is tested immediately (short-term recall) and again after 20 minutes (long-term recall). | Month 6 |
| Episodic memory between groups | California Verbal Learning Test--Second Edition (CVLT): in this word list recall and recognition test, the examiner reads a list of 16 nouns aloud at one-second intervals in a fixed order over five learning trials. The participant is asked to recall as many words as possible in any order (free recall). If subjects "cluster" words from each category, they are presumably using semantic organization. Free recall is tested immediately (short-term recall) and again after 20 minutes (long-term recall). | Month 12 |
| Episodic memory between groups | California Verbal Learning Test--Second Edition (CVLT): in this word list recall and recognition test, the examiner reads a list of 16 nouns aloud at one-second intervals in a fixed order over five learning trials. The participant is asked to recall as many words as possible in any order (free recall). If subjects "cluster" words from each category, they are presumably using semantic organization. Free recall is tested immediately (short-term recall) and again after 20 minutes (long-term recall). | Month 18 |
| Episodic memory between groups | California Verbal Learning Test--Second Edition (CVLT): in this word list recall and recognition test, the examiner reads a list of 16 nouns aloud at one-second intervals in a fixed order over five learning trials. The participant is asked to recall as many words as possible in any order (free recall). If subjects "cluster" words from each category, they are presumably using semantic organization. Free recall is tested immediately (short-term recall) and again after 20 minutes (long-term recall). | Month 24 |
| ID | Term |
|---|---|
| D011618 | Psychotic Disorders |
| D001523 | Mental Disorders |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
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