Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| AS | Other Identifier | UW Madison | |
| UWMSN | SMPH | DFMCH Departmen | Other Identifier | UW Madison | |
| Protocol Version 12/15/2025 | Other Identifier | UW Madison |
Not provided
Not provided
Not provided
for the summer, continue enrollment this fall
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this observational study is to compare the effectiveness of air surveillance and to better understand the relationship between household transmission and viruses detected in the air.
Participants will provide nasal swabs and have an air sample surveillance device installed in their home.
The purpose of ORCHARDS-AIR is to utilize air surveillance in participant homes in conjunction with individually collected nasal specimens to assess their concordance and evaluate the significance of airborne detection with household transmission of common respiratory pathogens such as influenza and SARS-CoV-2.
The researchers postulate that households with documented and probable respiratory pathogen transmission will have higher rates of in-home air surveillance detection. Students with more severe illnesses will be absent more often and spend more time at home, potentially leading to absenteeism being associated with greater air surveillance detections and intrahousehold transmission.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Students with ARI (acute respiratoy infection) | Experimental | Students with ARI and their household members will provide nasal swabs |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Nasal swab | Diagnostic Test | Participants will use a swab to collect nasal specimens |
|
| Measure | Description | Time Frame |
|---|---|---|
| Rate of virus detection | Participants will provide nasal swabs, which will be tested for a panel of viruses. | Day 0, Day 7, Day 14 |
| Rate of air sampling detection among families with documented transmission | Study team will collect and test air sampler filter for viruses. | Day 7, Day 14 |
| Rate of air sampling detection among families without documented transmission | Study team will collect and test air sampler filter for viruses. | Day 7, Day 14 |
| Survey of symptoms - day 0 | Qualitative survey of participants' symptoms and related activities. | Day 0 |
| Survey of symptoms - day 7 | Qualitative survey of participants' symptoms and related activities. | Day 7 |
| Survey of symptoms - day 14 | Qualitative survey of participants' symptoms and related activities. | Day 14 |
| Air sampler use survey | Qualitative survey about participants' use of the air sampler. | Day 7, Day 14 |
| Measure | Description | Time Frame |
|---|---|---|
| Number of absences | Participants will self-report whether they were absent from school during the study period. | 14 days |
Not provided
Inclusion Criteria - Students:
Exclusion Criteria - Students:
Inclusion Criteria - Household member:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Jonathan Temte, MD, PhD | University of Wisconsin, Madison | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Wisconsin-Madison | Madison | Wisconsin | 53705 | United States |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Indoor air quality monitor | Device | InBio Apollo ambient air sampler to be run in the home for the duration of study participation. Material from the air, like aerosols, dust particles, and other environmental material, are collected on sampler filler material. |
|