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Patient with transfusion depandant beta thalassemia with accumulation of iron in their body affect pituitary gland and gonades lead to impaired their functions .
detection of any abnormalities in pituitary gland hormones ( FSH , LH , serum prolactin ) gonadal hormones ( serum testesterone , antimullerian hormone , INSL3 , inhibin B hormone )
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| group 1 transfusion depandant beta thalassemia | transfusion depandant beta thalassemia 10 - 18 years old age gonadal function assesment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| serum inhibin B serum INSL3 serum AMH | Diagnostic Test | transfusion depandant beta thalassemia with measure gonadal function serum INSL3 serum inhibin B serum AMH |
|
| Measure | Description | Time Frame |
|---|---|---|
| gonadal function in transfusion depandant beta thalassemia | gonadal function assessment by Inhibin B hormone, INSL3 , serum testesterone that analysed in patient with age 10 - 18 year old for early detection of any abnormality | through study completion, an average of 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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transfusion depandant beta thalassemia male patients age 10 - 18 year old age
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Hager Saadeldin saadeldin, pediatric resident | Contact | +201065099621 | hagersaadeldin@gmail.com | |
| Ahmed Ahmed Moniur Hegab, Doctor | Contact | +201158744246 | ahmed1111mostafa@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| hager Saadeldin, resident | Sohag University | Principal Investigator |
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| ID | Term |
|---|---|
| D017086 | beta-Thalassemia |
| ID | Term |
|---|---|
| D013789 | Thalassemia |
| D000745 | Anemia, Hemolytic, Congenital |
| D000743 | Anemia, Hemolytic |
| D000740 | Anemia |
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| D006402 |
| Hematologic Diseases |
| D006425 | Hemic and Lymphatic Diseases |
| D006453 | Hemoglobinopathies |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |