Implications of Post-Operative Irrigation Fluid's Osmolarity on the Recurrence of Non-Muscle Invasive Bladder Cancer Following Transurethral Resection

Implications of Post-Operative Irrigation Fluid's Osmolarity on the Recurrence of Non-Muscle Invasive Bladder Cancer Following Transurethral Resection

This randomized controlled trial will evaluate the efficacy of three bladder irrigation solutions - distilled water (DW), normal saline (NS), and hypertonic saline (HS) - as continuous bladder irrigation (CBI) following transurethral resection of non-muscle invasive bladder cancer (NMIBC). Short term (6 months) recurrence and progression free survival are mainly evaluated.

Inclusion Criteria:

• Patients of non-muscle invasive urinary bladder urothelial carcinoma amenable for complete resection

Exclusion Criteria:

• Patients with post-operative complications that need prolonged irrigation.
• Patient who underwent incomplete resection during TURBT.
• When large bladder perforation was suspected during TURBT.
• Patients with chronic kidney disease.
• Muscle invasive disease