The Role of Microbiota in Pancreatic Cancer and Precursor Lesions

The Role of Microbiota in Pancreatic Cancer and Precursor Lesions

This is a prospective observational study aiming to investigate the microbiome in patients suspected of having pancreatic cancer. The purpose is to enhance diagnostic accuracy by developing screening protocols for high-risk individuals, identifying specific microbial biomarkers, and improving prognostic criteria to optimize treatment response.

Participants will be asked to complete a questionnaire, provide oral and fecal swabs, and-if clinically indicated-1-2 pancreatic biopsies will be collected.

Inclusion Criteria:

• Patients with a suspected lesion (solid/cystic) in the pancreas undergoing diagnostic or therapeutic endoscopic procedure
• Age of 18 years or above
• Signed informed consent form

Exclusion Criteria:

• Contraindications for endoscopic or surgical procedure, such as uncorrected coagulopathy