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This observational study aims to determine whether three blood test ratios - lactate-to-albumin, CRP-to-albumin, and procalcitonin-to-albumin - can predict in-hospital mortality among critically ill adults. The study includes all adult patients admitted in 2024 to the ICU Ward B at the Silesian Center for Heart Diseases (SCCS) in Zabrze. Researchers will analyze retrospective clinical and laboratory data from electronic medical records, including lab values collected at ICU admission, patient demographics, diagnoses, and outcomes. The biomarker ratios will be manually calculated in Excel and statistically evaluated. The main goal is to assess whether these ratios are associated with patient survival and to identify predictive cut-off values to support early risk stratification in the ICU setting.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Survivors | Critically ill adult patients admitted to the ICU who survived hospitalization and were discharged alive. | ||
| Non-Survivors | Critically ill adult patients admitted to the ICU who died during the course of hospitalization. |
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| Measure | Description | Time Frame |
|---|---|---|
| In-hospital mortality | All-cause in-hospital mortality among ICU patients during the index hospitalization. | 100 days from the date of ICU admission |
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Inclusion Criteria:
Exclusion Criteria:
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Adult patients admitted to the ICU. Data collected retrospectively from clinical records (AMMS system).
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Acute Medicine, Faculty of Medical Sciences in Zabrze, Medical University of Silesia in Katowice, Poland | Zabrze | Silesian Voivodeship | 41-800 | Poland |
The individual participant data (IPD) will not be shared due to the retrospective nature of the study and the use of sensitive patient health records. The dataset is not publicly available, and consent for external data sharing was not obtained from participants or their legal representatives.
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| ID | Term |
|---|---|
| D018805 | Sepsis |
| D012131 | Respiratory Insufficiency |
| D006323 | Heart Arrest |
| D012769 | Shock |
| D016638 | Critical Illness |
| D016757 | Death, Sudden, Cardiac |
| ID | Term |
|---|---|
| D007239 | Infections |
| D018746 | Systemic Inflammatory Response Syndrome |
| D007249 | Inflammation |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D020969 | Disease Attributes |
| D003645 | Death, Sudden |
| D003643 | Death |
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