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This retrospective study will be conducted by reviewing the medical records of hemiplegic patients who received botulinum toxin treatment between 2017 and 2020 at the Physical Medicine and Rehabilitation outpatient clinic of Istanbul Physical Medicine and Rehabilitation Training and Research Hospital. A total of 35 hemiplegic patients who underwent botulinum toxin injection and had at least two follow-up records (with a 6-month interval) will be included. Sociodemographic and clinical data, stroke-related characteristics, botulinum toxin dosage, injected muscle groups, medications, and comorbidities will be recorded. Functional assessments, including the Functional Independence Measure (FIM) and Brunnstrom stage, as well as spasticity evaluations using the Modified Ashworth Scale and the Global Spasticity Index, will be obtained from patient files.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| no intervention | Other | no intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Spasticity Severity: | Evaluated using the Modified Ashworth Scale (MAS) before and after botulinum toxin treatment. A decrease in MAS scores indicates a reduction in muscle tone and improved spasticity control. | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| Global Spasticity Index (GSI): | Changes in the GSI values before and after treatment will be analyzed to assess overall spasticity reduction. | Baseline |
| Functional Independence Measure (FIM): | Functional outcomes will be assessed using FIM scores. An increase in total FIM score indicates improved functional independence. |
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Inclusion Criteria:
Exclusion Criteria:
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The study population consists of hemiplegic patients aged 18-75 years who received botulinum toxin treatment for upper and/or lower extremity spasticity.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| İstanbul Physical Medicine and Rehabilitation Research and Training Hospital | Recruiting | Istanbul | Bahcelievler | 34147 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D006429 | Hemiplegia |
| ID | Term |
|---|---|
| D010243 | Paralysis |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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| Baseline |
| Brunnstrom Stage: | Motor recovery stages will be evaluated according to the Brunnstrom classification, with higher stages reflecting greater motor improvement. | Baseline |
| Injected Muscle Groups and Dosage: | The relationship between injected muscles, total botulinum toxin dosage, and clinical response will be analyzed to identify patterns associated with greater therapeutic benefit. | Baseline |
| D013568 |
| Pathological Conditions, Signs and Symptoms |