This is an observational study to evaluate hardware related and oncologic outcomes in adult patients with primary and metastatic spine disease undergoing separation surgery followed by radiation treatment.

This study is being done to collect information about patients undergoing separation surgery followed by radiation for the treatment of primary and metastatic spine disease. Participants will be asked to complete some patient reported outcome questionnaires and researchers will collect information from medical records to evaluate oncologic and hardware related outcomes.

Inclusion Criteria:

• Diagnosis of primary or metastatic disease to the spine who undergo surgical decompression and stabilization followed by radiation therapy

Exclusion Criteria:

• Inability to obtain a standard MRI or CT / CT myelogram for radiation treatment planning and dosimetry
• Inability to receive radiation treatment.
• Patients under 18 years of age

The study population will be comprised of patients with primary and metastatic spine disease who undergo surgery followed by radiation therapy.

Patients may be enrolled regardless of previous local or systemic treatments received prior to enrollment in this registry.

Patients may be enrolled regardless of other current local or systemic treatments of disease extent.