A Clinical Study Conducted in the Bangkok, Thailand Area, to Investigate the Clinical Efficacy of a New Toothpaste

A Randomized Single-center, Double-blind, Two-cell Parallel-group Clinical Study Conducted in the Bangkok, Thailand Area, to Investigate the Clinical Efficacy of a New Toothpaste Containing 0.454% Stannous Fluoride as Compared to a Regular Fluoride Toothpaste Containing 0.76% Sodium Monofluorophosphate in Controlling Oral Malodor 12 Hours Post-brushing Overnight After 3 Weeks of Twice a Day (Morning and Evening) Product Use.

To investigate the clinical efficacy of a new toothpaste containing 0.454% stannous fluoride as compared to a regular fluoride toothpaste containing 0.76% sodium monofluorophosphate on oral malodor reduction via organoleptic scores 12 hours post-brushing overnight after 3 weeks of twice a day (morning and evening) product use.

Inclusion Criteria:

• Male and female adults between the ages of 18-70 (inclusive)
• Subjects must be in general good health
• Subjects must be in good oral health based on self-assessment
• Subjects must be available for the duration of the study for all time point assessments
• Subjects were required to possess a minimum of 20 natural uncrowned teeth (excluding third molars)
• Subjects were required to sign an Informed Consent form
• No known history or allergies to personal care/consumer products or their ingredients.

Exclusion Criteria:

• Participated in any other oral clinical studies during the duration of this study
• Had full or partial (upper or lower) dentures
• Women who are pregnant or lactating (breast feeding)
• Use of tobacco products, (5) History of allergies to common mouthwash ingredients
• Use of phenolic flavored products, such as mint flavored candies and chewing gum the morning of the study of during the sampling periods
• Immune compromised individuals (HIV, AIDS, immune suppressive drug therapy
• Individuals who, due to medical conditions cannot go without eating or drinking for the post use treatment evaluation time points (6-hours plus overnight).