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This 3-week clinical study was designed to investigate the clinical efficacy on oral malodor of a 0.454% stannous fluoride toothpaste with nitrate and pyrophosphate (referred to as SNAP) compared to Colgate Cavity Protection Toothpaste containing 0.76% sodium monofluorophosphate 12 hours post-brushing after 3 weeks of product use.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group I | Experimental | Brushing twice daily in the morning and evening with 2 minutes each time |
|
| Group II | Active Comparator | Brushing twice daily in the morning and evening with 2 minutes each time |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| test product | Drug | toothpaste containing 0.45% stannous fluoride |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Organoleptic Oral Malodor Evaluations | The measured levels of oral malodor will be expressed in organoleptic scales (1-9) | Oral malodor evaluations at baseline & 3 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Deyu Hu, DDS,MS | West China Dental Institute of Chengdu | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| West China Dental Institute of Chengdu | Chengdu | Sichuan | 610041 | China |
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| ID | Term |
|---|---|
| D035061 | Control Groups |
| ID | Term |
|---|---|
| D015340 | Epidemiologic Research Design |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D012107 | Research Design |
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| Control product |
| Drug |
toothpaste containing 0.76% sodium monofluorophosphate |
|
| D008722 | Methods |