Novel DBS Device in Parkinson's Disease | NCT07213999

ID	Type	Description	Link
R21NS111214-01	U.S. NIH Grant/Contract		View source

Name	Class
National Institute of Neurological Disorders and Stroke (NINDS)	NIH

Novel DBS Device in Parkinson's Disease | NCT07213999 | Trialant

Description Module

Arms/Interventions Module

Label	Type	Description	Intervention Names
Neural recorder	Experimental		Device: Novel neural recorder

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Novel neural recorder	Device	The neural recorder does not suffer saturation from stimulation artifacts, allowing circuits to record neural signals with higher precision.	Neural recorder

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Wireless 9-axis inertial measurement unit (IMU) with 3-axis accelerometer, gyroscope, and magnetometer will quantitatively measure the activity of neurons when high or low stimulation frequency is used.	The investigators will compare the activity of neurons when high or low stimulation frequency is used, when stimulation is delivered ipsilaterally or contralaterally, and when different temporal patterns of DBS pulses are used within the constraints of standard clinical practice.	For the duration of the participant's' DBS surgery.

Contacts/Locations Module

Facility	Status	City	State	ZIP	Country	Contacts
University of Minnesota Medical Center		Minneapolis	Minnesota	55455	United States

References Module

Citations

PubMed Identifier	Type	Citation	Retractions
18329019	Background	Tabbal SD, Ushe M, Mink JW, Revilla FJ, Wernle AR, Hong M, Karimi M, Perlmutter JS. Unilateral subthalamic nucleus stimulation has a measurable ipsilateral effect on rigidity and bradykinesia in Parkinson disease. Exp Neurol. 2008 May;211(1):234-42. doi: 10.1016/j.expneurol.2008.01.024. Epub 2008 Feb 14.
17230483	Background	Nakamura K, Christine CW, Starr PA, Marks WJ Jr. Effects of unilateral subthalamic and pallidal deep brain stimulation on fine motor functions in Parkinson's disease. Mov Disord. 2007 Apr 15;22(5):619-26. doi: 10.1002/mds.21300.

Label	URL
Related Info	View source

Condition Browse Module

ID	Term
D010300	Parkinson Disease

ID	Term
D020734	Parkinsonian Disorders
D001480	Basal Ganglia Diseases
D001927	Brain Diseases
D002493	Central Nervous System Diseases

27534393

Background

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