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This clinical study is a single-center, randomized, split-face, on-site controlled trial conducted at Shanghai China-Norm Quality Technical Service Co., Ltd. The primary objective is to evaluate the efficacy of Eucerin Ultrasensitive Repair Intensive Source Serum in providing instant and long-lasting (24-hour) soothing and repairing effects under induced redness conditions. The design involves recruiting 30 healthy Chinese female subjects aged 18-60 years, who meet stringent inclusion/exclusion criteria, including absence of skin conditions and no recent participation in similar studies. Redness is induced using 50% Glycolic Acid on the entire face and tape stripping on both forearms.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Facial Test Arm | Other |
| |
| Facial Control Arm | No Intervention | ||
| Arm Test Arm | Other |
| |
| Arm Control Arm | No Intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Facial serum application | Other | The trained technician will apply the 0.3g-0.4g investigational products on the subject's half face. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Skin Erythema Index via Mexameter® MX 18 | From Baseline to 24-hour after product repeat application | |
| Colorimetry (avalue) via Chromameter CM26dG * | from Baseline to 24-hour after product repeat application | |
| Skin Scaliness (Desquamation) via Squamescan® 850A | from Baseline to 24-hour after product repeat application | |
| Forearm Skin Redness (avalue) via Cross-Polarized Light Imaging * | The a*value is a parameter in the CIELAB color space (also known as Lab) that quantifies a color's position along the red-green axis . | From Baseline to 24-hour after product repeat application |
| Facial Skin Redness and Colorimetry (a* value) via VISIA-CRP Imaging | from Baseline to 24-hour after product repeat application | |
| Skin Surface Evenness (SEsc) via UV Video Capture and SELS Analysis | from Baseline to 24-hour after product repeat application |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shanghai China-norm Quality Technical Service Co., Ltd. | Shanghai | Shanghai Municipality | 200072 | China |
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| ID | Term |
|---|---|
| D004890 | Erythema |
| ID | Term |
|---|---|
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D012877 | Skin Manifestations |
| D012816 | Signs and Symptoms |
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| Forearm serum application | Other | The trained technician will apply the (2mg±0.1mg)/cm² investigational products on the subject's forearm. |
|
| D013568 | Pathological Conditions, Signs and Symptoms |