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This registry at University Hospital Düsseldorf collects retrospective and prospective (from 2019 onward) data on patients undergoing electrophysiological studies (EPS), catheter ablation, and electrical cardioversion. The primary goal is to evaluate safety, efficacy, and clinical outcomes of these standard procedures in routine care. Data will be used for quality assurance and to identify prognostic patient- and procedure-related factors.
This is a single-center observational registry including all patients treated with EPS, catheter ablation, or electrical cardioversion at the Department of Cardiology, Pneumology, and Angiology, University Hospital Düsseldorf. Retrospective data from 2011 onward and prospective data from 2015 onward are collected.
The registry systematically records demographic data, comorbidities, laboratory and imaging results, procedural details, and follow-up outcomes. Patients are routinely followed at 1, 3, 6, 12, and 24 months after the procedure. Additional follow-up may be performed by telephone interview with patients or referring physicians to improve data quality.
Primary endpoints focus on safety (peri- and postprocedural complications, late adverse events) and efficacy (recurrence of arrhythmias, need for repeat procedures, pacemaker implantation, or new medications). Secondary endpoints include hospitalization and all-cause mortality.
Participation does not alter routine diagnostic or therapeutic decisions, and no additional invasive procedures are performed. Data will be used for quality assurance and to improve understanding of prognostic factors, with the ultimate aim of optimizing future patient care.
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| Measure | Description | Time Frame |
|---|---|---|
| Periprocedural and postprocedural safety events | All cardiovascular adverse events or complications occurring during hospitalization and late complications after discharge related to EPS, ablation, or electrical cardioversion. | Up to 24 months after procedure |
| Clinical efficacy outcomes | Procedural success, recurrence of arrhythmias or symptoms, and need for repeat EPS/cardioversion, additional medication, or device implantation (e.g., pacemaker). | Up to 24 months after procedure |
| Measure | Description | Time Frame |
|---|---|---|
| All-cause mortality | Death from any cause during follow-up. | Up to 24 months after procedure |
| All-cause hospitalization | Any hospital admission for cardiovascular or non-cardiovascular reasons during follow-up |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with heart rhythm disorders
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Obaida Rana, MD | Contact | +492118118800 | obaida.rana@med.uni-duesseldorf.de | |
| Lisa Dannenberg, MD | Contact | + 49211 81 05315 | LisaKristina.Dannenberg@med.uni-duesseldorf.de |
| Name | Affiliation | Role |
|---|---|---|
| Malte Kelm, MD | Division of Cardiology, Pulmonary Disease and Vascular Medicine at University Hospital Duesseldorf | Study Chair |
| Obaida Rana, MD | Division of Cardiology, Pulmonary Disease and Vascular Medicine at University Hospital Duesseldorf |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Duesseldorf | Recruiting | Düsseldorf | 40225 | Germany |
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| D001282 | Atrial Flutter |
| D013617 | Tachycardia, Supraventricular |
| D017180 | Tachycardia, Ventricular |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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Plasma
| Up to 24 months after procedure |
| D013568 |
| Pathological Conditions, Signs and Symptoms |
| D013610 | Tachycardia |
| D000075224 | Cardiac Conduction System Disease |