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| Name | Class |
|---|---|
| Department of Internal Medicine I - Cardiology | UNKNOWN |
| KKS -Kardiologisches Klinisches Studienzentrum | UNKNOWN |
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Questionnaire - Supraventricular arrhythmia | Questionnaire about triggers and stops of supra ventricular arrhythmia | ||
| Extended ECG - Effect of electrophysiological ablation | Extended signal-averaged ECGs in patients with ablation of supra ventricular ablation |
| |
| Extended ECG - Virtual atrial Electrocardiogram | Improve visualisation of atrial arrhythmia by means of extended signal-averaged ECGs |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Recording of an extended high-resolution ECG | Device | Recording of an extended high-resolution ECG |
|
| Measure | Description | Time Frame |
|---|---|---|
| Triggers of supraventricular arrhythmia | Anamnestic and ECG measured triggers of supra ventricular arrhythmia | 2 years |
| Measure | Description | Time Frame |
|---|---|---|
| P-Wave duration | Characteristics and changes by ablation of atrial electrical activation will be analyzed by means of signal-averaged P-Wave parameters | 2 years |
| P-Wave amplitude | Characteristics and changes by ablation of atrial electrical activation will be analyzed by means of signal-averaged P-Wave parameters |
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Inclusion Criteria:
Exclusion Criteria:
Exclusion criteria for study section Questionnaire:
- Competing clinically present arrhythmias, including relevant supra- and ventricular extrasystole (>5%/die).
Exclusion criteria for study section Extended high-resolution ECG:
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Cohort for study section Questionnaire: 1000 evaluable questionnaires are targeted. Every suitable potential respondent will be invited and interviewed during the data collection period. After 400 subjects in the questionnaire section, an interim evaluation will be carried out.
Cohort for study section extended high-resolution ECG: In a feasibility study, signal-enhanced ECGs will be recorded in a subgroup of cohort before, during and after ablation with the aim of non-invasive ECG diagnostics. There are no published empirical values for this and 250 subjects will be notified. After 100 subjects in the high-resolution ECG section, an interim evaluation will be carried out.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Matthias D Zink, MD | Contact | 00492418035113 | mzink@ukaachen.de | |
| Michael Gramlich | Contact | mgramlich@ukaachen.de |
| Name | Affiliation | Role |
|---|---|---|
| Matthias D Zink, MD | RWTH Aachen University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| RWTH Aachen University | Recruiting | Aachen | North Rhine-Westphalia | 52074 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41640583 | Derived | Fantazi N, Hermans BJM, Zeemering S, Berbers J, Emrani M, Napp A, Marx N, Gramlich M, Schotten U, Zink MD. Acute effect of cryoballoon pulmonary vein isolation on the signal-averaged P-wave. Front Cardiovasc Med. 2026 Jan 20;12:1728939. doi: 10.3389/fcvm.2025.1728939. eCollection 2025. |
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Data can be shared on reasonable request after data is already published
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| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
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| 2 years |
| P-Wave PQ time (time mesaured from begin of P-wave to begin of Q-Peak) | Characteristics and changes by ablation of atrial electrical activation will be analyzed by means of signal-averaged P-Wave parameters | 2 years |
| Signal-averaged P-Wave sample entropy | Characteristics and changes by ablation of atrial electrical activation will be analyzed by means of signal-averaged P-Wave parameters | 2 years |
| Signal-averaged P-Wave shannon entropy | Characteristics and changes by ablation of atrial electrical activation will be analyzed by means of signal-averaged P-Wave parameters | 2 years |
| Signal-averaged P-Wave complexity | Characteristics and changes by ablation of atrial electrical activation will be analyzed by means of signal-averaged P-Wave parameters | 2 years |
| Visualisation of a signal-averaged P-Wave before and after catheter ablation with qualitative review of morphology | By recording of unfiltered high-resolution ECG and calculation of a signal-averaged P-Wave and other post-processing techniques a better visualization of ongoing arrhythmia shall be achieved | 2 years |
| D013568 |
| Pathological Conditions, Signs and Symptoms |