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Considering the remarkable increase of the fitness programs, the purpose of this study was to assess and compare the effect of Crossfit (CF) and periodized resistance (RT) trainings on inflammatory/oxidative responses in untrained individuals.
Twenty-four participants (20 men and 4 women, age= 25.7 ± 2.2 years, BMI= 25.7 kg.m-2) were randomly assigned into 12 weeks of these trainings with a rate of five sessions/week. Before and after intervention, participants anthropometric data and graded exercise tests were performed. Before (pre), immediately after (post) and 60min after test (p60) a 20mL venous blood sample were drawn for a later measure of c-reactive protein (CRP), interleukin 1 beta (IL-1ß), tumor necrosis factor alpha (TNF-α), interleukin 6 (IL-6), interleukin 10 (IL-10), thiobarbituric acid reactive substances (TBARS), antioxidant enzymes catalase (CAT) and glutathione peroxidase (GPx).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CrossFit | Experimental | High intensity functional training |
|
| Resistance | Experimental | Periodized resistance training |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 12 week training | Behavioral | Anti-inflammatory and oxidative environment following 12-weeks of CF training by evaluating inflammatory markers and oxidative precursors in untrained participants |
| Measure | Description | Time Frame |
|---|---|---|
| Inflammatory marker | c-reactive protein (CRP), | Participants data were performed in one day before beginning the 12 week intervention and one day after the last session |
| Inflammatory marker | interleukin 1 beta (IL-1ß) | Participants data were performed in one day before beginning the 12 week intervention and one day after the last session |
| Inflammatory marker | tumor necrosis factor alpha (TNF-α) | Participants data were performed in one day before beginning the 12 week intervention and one day after the last session |
| Inflammatory marker | interleukin 6 (IL-6) | Participants data were performed in one day before beginning the 12 week intervention and one day after the last session |
| Inflammatory marker | interleukin 10 (IL-10) | Participants data were performed in one day before beginning the 12 week intervention and one day after the last session |
| Oxidative stress | thiobarbituric acid reactive substances (TBARS) | Participants data were performed in one day before beginning the 12 week intervention and one day after the last session |
| Oxidative stress | antioxidant enzymes catalase (CAT) | Participants data were performed in one day before beginning the 12 week intervention and one day after the last session |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institut Supérieur du Sport et de l'Education Physique de Ksar-Saïd | Aryanah | Ariana Governorate | 2073 | Tunisia |
Under negotation
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| ID | Term |
|---|---|
| D007249 | Inflammation |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| 12 week training | Behavioral | Anti-inflammatory and oxidative environment following 12-weeks of resistance training by evaluating inflammatory markers and oxidative precursors in untrained participants |
|
| Oxidative stress | glutathione peroxidase (GPx) | Participants data were performed in one day before beginning the 12 week intervention and one day after the last session |