The aim of the study is to assess prevalence of frailty among renal transplant recipients in Alexandria University Hospitals and to study the relation between frailty and chronic allograft dysfunction.

With respect to correlates of frailty, although higher comorbidity burden is also a risk factor for frailty among KT candidates, frailty can also occur in the setting of lower comorbidity burdens. Diabetes and serum albumin concentration are also associated with frailty among prevalent dialysis patients.

In addition, individuals with CKD and ESKD who are frail are also more likely to have cognitive impairment and sarcopenia, or low muscle mass, than their non-frail counterparts

Inclusion Criteria:

• Renal transplanted patients with GFR more than 30

Exclusion Criteria:

• Mentally or physically unfit patients.
• Amputation of lower limb.
• Active neoplasia, chronic liver disease, previous immunological disease.
• Psychiatric disorders.
• Pregnancy.