Hystrectomy is a surgical procedure that involves removal of uterus from the body of patient using a lower abdominal incision. This is an extremely painful procedure which causes discomfort and greatly increases opioids consumption in the peri-operative period. This can be reduced by using nerve blocks such as Erector spinae plane block.

Total abdominal hystrectomy is associated with significant pain due to large abdominal incision and significant surgical dissection. This greatly increases the consumption of Opioid in the peri-operative period. High dose opioid consumption is associated with constipation, nausea, vomiting and respiratory depression. This significantly hampers post operative recovery. Fascial plane blocks such as Erector spinae block provides significant analgesia greatly reducing opioid consumption and there by reducing the associated side effects.

Inclusion Criteria:

• American Society of Anesthesiologists (ASA) class: I, II and III .
• Elective Hysterectomy under General Anesthesia.

Exclusion Criteria:

• Lack of consent
• Body mass index >35 kg/m2
• Allergic to study medicine
• Opioid abuse or misuse disorder
• Chronic pain