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This study aims to evaluate the effects of erector spinae plane block on intraoperative fentanyl consumption in patients undergoing abdominal hysterectomy under general anesthesia.
To our knowledge, no study in the literature demonstrates this effect.
This study will be performed in Fayoum University hospital after approval of the institutional ethics committee and written informed consent. This study will be conducted as a prospective, randomized, double-blind, parallel-group clinical trial.
Inclusion criteria:
Exclusion criteria:
The patients will be randomized into two groups: ESP block group who will receive preoperative US-guided bilateral ESP block with 20 ml of bupivacaine 0.25% on each side and Control group who will undergo the same procedure but with an injection of 20 ml of saline on a 1:1 ratio using a computer-generated random table. The patient's assigned group information will be elicited from a sealed opaque envelope by the anesthesiologist who will perform the ESP block and will not be involved in further data collection or patient care. The patients and both the surgical and anesthesia teams, who are responsible for patient care and data collection are blinded from the group assignments.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ESP block | Active Comparator | The patients will be randomized into two groups: ESP block group who will receive preoperative US-guided bilateral ESP block with 20 ml of bupivacaine 0.25% on each side |
|
| Control | Sham Comparator | The patients will be randomized into two groups: ESP block group who will receive preoperative US-guided bilateral ESP block with 20 ml of saline on each side |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ESP block | Procedure | ESP block group who will receive preoperative US-guided bilateral ESP block with 20 ml of bupivacaine 0.25% on each side |
|
| Measure | Description | Time Frame |
|---|---|---|
| The total intraoperative fentanyl consumption (μg) | the total doses of intraoperative fentanyl consumption in (μg) | operative time in hours |
| Measure | Description | Time Frame |
|---|---|---|
| intraoperative sevoflurane consumption (ml) | intraoperative sevoflurane consumption (ml) | operative time in hours |
| post-operative fentanyl consumption in (μg) | post-operative fentanyl consumption in the first 24 hours (μg) |
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Inclusion Criteria:
-
Inclusion criteria:
Exclusion Criteria:
Patient refusal.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fayoum University Hospital | Al Fayyum | 63511 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32547172 | Background | Boules ML, Goda AS, Abdelhady MA, Abu El-Nour Abd El-Azeem SA, Hamed MA. Comparison of Analgesic Effect Between Erector Spinae Plane Block and Transversus Abdominis Plane Block After Elective Cesarean Section: A Prospective Randomized Single-Blind Controlled Study. J Pain Res. 2020 May 19;13:1073-1080. doi: 10.2147/JPR.S253343. eCollection 2020. | |
| 23945838 |
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no plane
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| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
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| ID | Term |
|---|---|
| D000765 | Anesthesia, Conduction |
| ID | Term |
|---|---|
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
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This study will be conducted as a prospective, randomized, double-blind, parallel-group clinical trial.
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|
| the first 24 hours postoperative |
| VAS score | visual analog score | the first 24 hours postoperative |
| mean operative times (min) | operative times duration in (min) | operative times in (min) |
| Azari L, Santoso JT, Osborne SE. Optimal pain management in total abdominal hysterectomy. Obstet Gynecol Surv. 2013 Mar;68(3):215-27. doi: 10.1097/OGX.0b013e31827f5119. |
| 31118757 | Result | Hamed MA, Goda AS, Basiony MM, Fargaly OS, Abdelhady MA. Erector spinae plane block for postoperative analgesia in patients undergoing total abdominal hysterectomy: a randomized controlled study original study. J Pain Res. 2019 Apr 30;12:1393-1398. doi: 10.2147/JPR.S196501. eCollection 2019. |
| 37277703 | Derived | Hamed MA, Boules ML, Mahmoud MAEM, Abdelghaffar RA. The effect of erector spinae plane block on fentanyl consumption during open abdominal hysterectomy: a randomised controlled study. BMC Anesthesiol. 2023 Jun 5;23(1):194. doi: 10.1186/s12871-023-02156-3. |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |