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The goal of this clinical trial is to determine if there is a difference in eyelid temperature after low-level light therapy (LLLT) in individuals with different amounts of skin pigmentation and dry eye/meibomian gland disease. Participants will have 3 fifteen minute in office LLLT therapy sessions over a period of approximately 7 to 14 days.
The primary objective of the study is to determine if there is a difference in the thermal effect of low-level light therapy (LLLT) in individuals with different skin pigmentation (Fitzpatrick skin type I-IV verses Fitzpatrick skin type V-VI) using a clinically available 633nm LLLT system, the Epi-C-Plus (Espansione group, Bologna, Italy).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Fitzpatrick skin tone I-IV | Experimental | Individuals with skin tones I-IV on the Fitzpatrick scale will receive low-level light therapy |
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| Fitzpatrick skin tone V-VI | Experimental | Individuals with skin tones V-Vi on the Fitzpatrick scale will receive low-level light therapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Three 15-minute low-level light therapy sessions using Light Emitting Diodes of wavelength 633nm (Essilor epi-c plus). | Device | A mask with Light Emitting Diodes wavelength 633nm will be placed over closed eyes for 15 minutes. |
| Measure | Description | Time Frame |
|---|---|---|
| Eyelid temperature | Eyelid temperature will be measured before and after 15 minutes of low-level light therapy at the baseline visit. |
| Measure | Description | Time Frame |
|---|---|---|
| Ocular Surface Disease Index Questionnaire | After 3 low-level light therapy treatment sessions through study completion, an average of 1 week. | |
| Tear break up time | After 3 low-level light therapy treatment sessions through study completion, an average of 1 week. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Eric Ritchey, OD, PhD | Contact | 713-743-1933 | erritche@central.uh.edu | |
| Rachel Redfern, OD, PhD | Contact | 713-743-1943 | rredfern@uh.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Houston College of Optometry | Recruiting | Houston | Texas | 77204 | United States |
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| ID | Term |
|---|---|
| D015352 | Dry Eye Syndromes |
| D000080343 | Meibomian Gland Dysfunction |
| ID | Term |
|---|---|
| D007766 | Lacrimal Apparatus Diseases |
| D005128 | Eye Diseases |
| D005141 | Eyelid Diseases |
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