Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Assiut University | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
Correlation between optical coherence tomography and multifocal electroretinogram findings with visual acuity in patients with macular dystrophy.
Macular dystrophies cause progressive central vision loss, but the relationship between structural retinal changes (OCT) and functional deficits (mf-ERG) with visual outcomes remains poorly understood. Current clinical assessment relies primarily on visual acuity, which inadequately reflects retinal damage or predicts disease progression. This knowledge gap limits prognostic accuracy and optimal patient management. Recent advances in OCT and mf-ERG technology provide an opportunity to establish robust structure-function correlations. Understanding these relationships will enhance patient care through improved prognosis, standardized monitoring protocols, and better clinical trial outcome measures for macular dystrophy patients.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| OCT ,mFERG,VA test | Diagnostic Test | retinal photography by OCT, VA measurement, and mfERG test |
| Measure | Description | Time Frame |
|---|---|---|
| BCVA (best corrected visual acuity) | BCVA was recorded in 30 eyes of 30 patients with macular dystrophy. | Day 1/month 3 |
| CMT (central macular thickness) μm Central macular thickness measurement using optical coherence tomography | CMT (central macular thickness) in μm in 30 eyes of 30 patients with macular dystrophy Central macular thickness measurement using optical coherence tomography. | Day1/month 3 |
| mf-ERG amplituide nV/deg2 | mf-ERG amplitude nV/deg² in 30 eyes of 30 patients with macular dystrophy multifocal electroretinogram amplitude measurement using the mf-ERG machine | Day 1/month 6 |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
All patients diagnosed with macular dystrophy during the period of the study
Not provided
| ID | Term |
|---|---|
| D008268 | Macular Degeneration |
| ID | Term |
|---|---|
| D012162 | Retinal Degeneration |
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided