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Correlation between changes observed in OCT and VA in patients with retinal vein occlusion whether the patient's VA improves when macular edema improves in OCT or not ??
Central retinal vein occlusion (CRVO) is a common retinal vascular disorder. Clinically, CRVO presents with variable visual loss; fundus may show retinal hemorrhages, dilated tortuous retinal veins, cotton-wool spots, macular edIn view of the devastating complications associated with the severe form of CRVO, number of classifications were described. All of classifications take into account the area of retinal capillary nonperfusion and development of neovascular complications.
CRVO can be divided into 2 clinical types, ischemic and nonischemic. In addition, a number of patients may have an intermediate presentation with variable clinical course. On initial presentation, it may be difficult to classify a given patient, since CRVO may change with time.
A number of clinical and ancillary investigative factors are taken into account for classifying CRVO:
Nonischemic CRVO is milder form of disease. It may present with good vision, few retinal hemorrhages and cotton-wool spots, no relative afferent pupillary defect, and good perfusion to the retina. Nonischemic CRVO may resolve fully with good visual outcome or may progress to the ischemic type.
Ischemic CRVO is the severe form of the disease. CRVO may present initially as the ischemic type, or it may progress from nonischemic. Usually, ischemic CRVO presents with severe visual loss, extensive retinal hemorrhages and cotton-wool spots, presence of relative afferent pupillary defect, poor perfusion to retina, and presence of severe electroretinographic changes. In addition, patients may end up with neovascular glaucoma and a painful blind eye.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients with macular edema due to RVO | assessment of visual acuity using Landolt chart and follow up of macular edema using OCT |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| OCT | Device | Assessment of macular edema secondary to retinal vein occlusion usin optical coherence tomography and its correlation with visual acuity |
|
| Measure | Description | Time Frame |
|---|---|---|
| Macular edema assessment | Macular edema assessed by OCT in microns | 5 minutes |
| Visual acuity assessment | Visual acuity assessment through Landolt chart | 5 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Causes of non improvement of visual acuity in patients with resolving macular edema | To detect causes of visual non improvement with visual acuity measured through Landolt chart in patients with resolving macular edema measured by OCT device in microns | 5 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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in patients developing retinal vein occlusion for following up their changes in OCT & VA
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Samir Y Saleh, professor | Contact | 00201003304320 | samir.abouelail@med.au.edu.eg | |
| waleed s Mohamed, lecturer | Contact | 002012223971491 | walidibrahim72@aun.edu.eg |
| Name | Affiliation | Role |
|---|---|---|
| Abdelsalam a Mohamed, ass. prof. | Assiut University | Study Chair |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 9109757 | Background | Natural history and clinical management of central retinal vein occlusion. The Central Vein Occlusion Study Group. Arch Ophthalmol. 1997 Apr;115(4):486-91. doi: 10.1001/archopht.1997.01100150488006. | |
| 6877778 | Background | Hayreh SS. Classification of central retinal vein occlusion. Ophthalmology. 1983 May;90(5):458-74. doi: 10.1016/s0161-6420(83)34530-9. |
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| ID | Term |
|---|---|
| D012170 | Retinal Vein Occlusion |
| ID | Term |
|---|---|
| D012164 | Retinal Diseases |
| D005128 | Eye Diseases |
| D020246 | Venous Thrombosis |
| D013927 | Thrombosis |
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| 7829175 | Background | Hayreh SS. Retinal vein occlusion. Indian J Ophthalmol. 1994 Sep;42(3):109-32. |
| 9349161 | Background | Williamson TH. Central retinal vein occlusion: what's the story? Br J Ophthalmol. 1997 Aug;81(8):698-704. doi: 10.1136/bjo.81.8.698. No abstract available. |
| 8154523 | Result | Hayreh SS, Zimmerman MB, Podhajsky P. Incidence of various types of retinal vein occlusion and their recurrence and demographic characteristics. Am J Ophthalmol. 1994 Apr 15;117(4):429-41. doi: 10.1016/s0002-9394(14)70001-7. |
| 18189152 | Result | Moschos MM, Moschos M. Intraocular bevacizumab for macular edema due to CRVO. A multifocal-ERG and OCT study. Doc Ophthalmol. 2008 Mar;116(2):147-52. doi: 10.1007/s10633-007-9110-9. Epub 2008 Jan 10. |
| 19052771 | Result | Gupta B, Grewal J, Adewoyin T, Pelosini L, Williamson TH. Diurnal variation of macular oedema in CRVO: prospective study. Graefes Arch Clin Exp Ophthalmol. 2009 May;247(5):593-6. doi: 10.1007/s00417-008-1011-4. Epub 2008 Dec 4. |
| D016769 |
| Embolism and Thrombosis |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |