Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Red Bull Athlete Performance Center | UNKNOWN |
Not provided
Not provided
Not provided
Not provided
This study is investigating whether taking sodium bicarbonate, a common supplement used by endurance athletes, can improve cycling performance during prolonged exercise and in a time trial. Sodium bicarbonate may help reduce muscle acidity, which could delay fatigue and improve performance. The goal of this study is to determine if this supplement can help athletes perform better during long, intense efforts like those seen in real competitions.
Participants in this study are well-trained cyclists who will complete two exercise trials in a laboratory setting. Each trial involves three hours of moderate cycling followed by a 20-30-minute time trial at maximum effort. Before each trial, participants will take either sodium bicarbonate or a placebo.
The study will measure performance outcomes, such as time trial results, as well as physiological responses, including heart rate, oxygen use, and muscle fatigue. Researchers hope to better understand how sodium bicarbonate can help endurance athletes and provide guidelines for its use in competitive sports.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo then Verum | Other | Placebo then Verum 3 hour low-intensity ride followed by a 16 km time trial for both conditions. Supplementation of Placebo or Verum before the exercise start. |
|
| Verum then Placebo | Other | Verum then Placebo 3 hour low-intensity ride followed by a 16 km time trial for both conditions. Supplementation of Placebo or Verum before the exercise start. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo then Verum | Dietary Supplement | Intake of 0.3 g/kg bodyweight of maltodextrin with hydrogel as placebo and 0.3 g/kg bodyweight of sodium bicarbonate with hydrogel as Verum |
| Measure | Description | Time Frame |
|---|---|---|
| Endurance performance | Difference in time trial performance (average power in watts) between placebo and verum condition | 20-30 minutes, immediately after completion of the time trial for each condition (Placebo and Verum), assessed on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Measure | Description | Time Frame |
|---|---|---|
| Difference in questionnaire score - gastrointestinal symptoms | Difference in questionnaire score gastrointestinal symptoms between placebo and verum condition (0-10, higher score indicates more severe symptoms). | 6.5 hours (rest, breakfast, every 30min during 3-hour low-intensity, after TT) for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Diabetes II.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Red Bull Athlete Performance Center | Thalgau | State of Salzburg | 5303 | Austria |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Double blinded two-intervention crossover study
Not provided
Not provided
Not provided
| Verum then Placebo | Dietary Supplement | Intake of 0.3 g/kg bodyweight of maltodextrin with hydrogel as placebo and 0.3 g/kg bodyweight of sodium bicarbonate with hydrogel as Verum |
|
| Difference in questionnaire score - Energy & Confidence | Difference in questionnaire score energy and confidence in time trial performance between placebo and verum condition (0-10, higher score indicates more Energy or Confidence in time trial performance). | 3 hours (every 30min during 3-hour low-intensity) for each condition (Placebo and Verum), assessed on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in questionnaire score - rate of perceived exertion | Difference in questionnaire score overall and legs only perceived exertion between placebo and verum condition (0-10, higher score indicates a higher degree of perceived exertion). | 3.5 hours (every 30min during 3-hour low-intensity, after TT) for each condition (Placebo and Verum), assessed on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in blood count | Difference in capillary blood count between placebo and verum condition | 6.5 hours (rest, every 30min during 3-hour low-intensity, after TT) for each condition (Placebo and Verum), assessed on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in pH & HCO3 kinetics | Difference in pH & HCO3 kinetics between placebo, verum and resting verum condition | 6.5 hours (rest, breakfast, every 30min during 3-hour low-intensity, after TT) for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in heart rate | Difference in heart rate (bpm) between placebo and verum condition | 3.5 hours, assessed continuously (every second) during 3 hour low-intensity and TT for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in oxygen uptake | Difference in oxygen uptake (ml/kg/min) between placebo and verum condition | 3 hours, assessed for 5 min every 30 min during 3 hour low-intensity for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in blood lactate concentration | Difference in blood lactate concentration (mmol/L) between placebo and verum condition. | 3.5 hours, assessed every 30 min during 3 hour low-intensity and after TT for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in substrate utilization | Difference in substrate utilization between placebo and verum condition. | 3 hours, assessed for 5 min every 30 min during 3 hour low-intensity for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in ventilation | Difference in ventilation (L/min) between placebo and verum condition | 3 hours, assessed for 5 min every 30 min during 3 hour low-intensity for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in core body temperature | Difference in core body temperature (°) between placebo and verum condition. | 3.5 hours, assessed continuously during 3 hour low-intensity and TT for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in muscle oxygenation | Difference in muscle oxygenation (SmO2) of the vastus lateralis between placebo and verum condition. | 3.5 hours, assessed continuously during 3 hour low-intensity and TT for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in glucose level | Difference in glucose level (mg/dl) between placebo and verum condition. | 24 hours, assessed continuously for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in sodium content | Difference in sodium content (mg/hr) between placebo and verum condition | 3.5 hours, assessed during 3 hour low-intensity and TT for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in sweat rate | Difference in sweat rate (L/hr) between placebo and verum condition. | 3.5 hours, assessed during 3 hour low-intensity and TT for each condition (Placebo and Verum), on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |
| Difference in next morning weight | Difference in weight (kg) measured in the morning of the test day and the following day (before breakfast after urination and defecation) | 24 hours, assessed in the morning for each condition (Placebo and Verum) and the following day, on test day 1 and test day 2 respectively, with a washout period of 3-7 days between appointments (test days). |