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| Name | Class |
|---|---|
| Poznan University of PhysED | INDIV |
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The purpose of this study was to verify the effect of 10-day sodium bicarbonate (NaHCO3) and placebo (PLA) supplementation on body composition, physical capacity, as well as concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.
Sodium bicarbonate (NaHCO3) was proposed as an ergogenic agent, because it improves high-intensity and resistance exercise performance. Until now the major limitation to NaHCO3 supplementation has been the gastrointestinal (GI) side effects. Therefore, this study aims to examine the effect of chronic, progressive- dose NaHCO3 ingestion on physical capacity, body composition and concentrations of the selected biochemical blood markers in trained athletes, in a randomised, double-blind, placebo-controlled crossover trial.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sodium bicarbonate | Experimental | Group taking oral NaHCO3 supplementation in a progressive-dose regimen. Interventions: The experimental procedure for each athlete included a 10-day NaHCO3 supplementation in a progressive-dose regimen in order to reduce the likelihood of gastrointestinal side effects (from 37.5 to 150 mg ∙ kg-1). NaHCO3 was administered in the form of unmarked disk-shaped tablets (Alkala T, SANUM, Poland). The tablets were ingested with at least 250 mL of water and could be either swallowed or dissolved in the mouth. On training days the supplements were taken in the morning, in the evening and 1.5 hours before training session. On rest days the supplements were taken in the morning, in the afternoon and in the evening. Between the 10-day NaHCO3 and PLA or a PLA and NaHCO3 treatments, a 14-day washout period was introduced. |
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| Placebo (maltodextrin) | Placebo Comparator | Group taking oral supplementation with placebo (maltodextrin). Interventions: The experimental procedure for each athlete included a 10-day placebo administration. Placebo was ingested with at least 250 mL of water. On training days the supplements were taken in the morning, in the evening and 1.5 hours before training session. On rest days the supplements were taken in the morning, in the afternoon and in the evening. Between the 10-day NaHCO3 and PLA or a PLA and NaHCO3 treatments, a 14-day washout period was introduced. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sodium bicarbonate supplementation | Dietary Supplement |
| ||
| Placebo treatment |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in aerobic capacity after sodium bicarbonate supplementation | The incremental cycling test (ICT) | Baseline and after 10 days |
| Changes in specific performance capacity after sodium bicarbonate supplementation | The CrossFit-specific physical fitness test: Fight Gone Bad (FGB) | Baseline and after 10 days |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in fat mass and fat free mass after sodium bicarbonate supplementation | Fat mass (kg) and fat free mass (kg) analysis | Baseline and after 10 days |
| Changes of red and white blood cell concentration in blood after sodium bicarbonate supplementation |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jan Jeszka, Professor | Department of Hygiene and Human Nutrition, Poznan University of Life Sciences, Poznan, Poland | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Poznan University of Life Sciences, ul.Wojska Polskiego 31 | Poznan | Wielkopolska | 60-624 | Poland |
Shared data will be exclusively related to the level recorded indicators (body composition, aerobic and anaerobic capacity indicators, levels of biochemical markers), without personal data. The data obtained will be attached to scientific publications, depending on the requirements of the journal
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| Dietary Supplement |
|
Red blood cells (RBC) [mln/mm³] and white blood cells (WBC) [mln/mm³] concentration analysis |
| Baseline and after 10 days |
| Changes in blood glucose and hemoglobin concentration after sodium bicarbonate supplementation | Hemoglobin (Hb) [g/dl] and glucose [g/dl] concentration analysis | Baseline and after 10 days |
| Changes in blood hematocrit levels after sodium bicarbonate supplementation | Hematocrit (HCT) [%] level analysis | Baseline and after 10 days |
| Changes of lactate and pyruvate concentration in blood after sodium bicarbonate supplementation | Lactate [mmol/L] and pyruvate [mmol/L] concentration analysis | Baseline and after 10 days |
| Changes of creatine kinase and lactate dehydrogenase activity in blood after sodium bicarbonate supplementation | Creatine kinase [U/L] and lactate dehydrogenase [U/L] activity analysis | Baseline and after 10 days |