Brain Areas of Cognitive Functions: a Study in Awake Surgery

Brain Areas of Cognitive Functions: a Study in Awake Surgery

This research project focuses on low-level cognitive functions such as perception (auditory, visual, etc.) and high-level cognitive functions (memory, language, temporal estimation, etc.). It aims to better understand the brain bases of these functions as well as their overlap (i.e., brain bases considered to be involved in different functions).

To this end, various cognitive tasks will be performed before and during awake brain surgery, allowing us to determine the involvement of different areas in the task being performed. Comparing performance between the pre-test and the intraoperative test will help determine the potential involvement of the tested area.

Inclusion Criteria:

• Patients with a brain tumor
• Aged 18 to 75 years
• Signed informed consent
• Vision that is corrected or adequate for the purposes of an experiment with visual stimuli
• Hearing that is corrected or adequate for the purposes of an experiment with auditory stimuli
• No known oculomotor disorder
• Person affiliated with or benefiting from a social security scheme.
• Free, informed, and written consent signed by the participant and the investigator (no later than the day of inclusion and before any examination required by the research)

Exclusion Criteria:

• Participants under protected status: guardianship, legal safeguard proceedings, or whose consent to participate in the experiment could be due to a severely altered psychological state, as determined by the medical team responsible for the surgery.
• History of neurological disease affecting the central nervous system (Parkinson's, Alzheimer's, history of stroke or cerebral infarction)
• Pregnant and/or breastfeeding women.