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| ID | Type | Description | Link |
|---|---|---|---|
| ID-RCB | Other Identifier | 2025-A01307-42 |
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This research project focuses on low-level cognitive functions such as perception (auditory, visual, etc.) and high-level cognitive functions (memory, language, temporal estimation, etc.). It aims to better understand the brain bases of these functions as well as their overlap (i.e., brain bases considered to be involved in different functions).
To this end, various cognitive tasks will be performed before and during awake brain surgery, allowing us to determine the involvement of different areas in the task being performed. Comparing performance between the pre-test and the intraoperative test will help determine the potential involvement of the tested area.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pré-End | No Intervention | The day before surgery, brain tumor patients will be offered long-form cognitive tests. If the results of the cognitive tests are not consistent with the literature, this suggests that the tumor is affecting pre-contact time perception. These patients will not be tested during surgery. | |
| Pré-Per | Experimental | The day before surgery, brain tumor patients will be offered long-form cognitive tests. If the results of the cognitive tests are consistent with the literature, the short-form cognitive tests will be offered during awake surgery. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Short version of cognitive testing during surgery | Behavioral | Cognitive testing in 3 blocks of 3 minutes during awake surgery |
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| Measure | Description | Time Frame |
|---|---|---|
| development of an atlas mapping the brain regions involved in each major cognitive function | Analysis of the percentage of "yes" responses during the intraoperative phase, taking into account the expected probability based on preoperative results. Preoperative performance data allows to determine an expected performance level during the intraoperative phase. | One day after the inclusion |
| Measure | Description | Time Frame |
|---|---|---|
| Number of tests | number of tests for which a brain area is considered to be involved during the analysis of the primary criterion for the pre-per group | One day after the inclusion |
| Location of brain tumors |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Franck Emmanuel ROUX, PHD | Contact | 05 61 77 93 81 | +33 | roux.F@chu-toulouse.Fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Service de Neurochirurgie, Hôpital Pierre Paul Riquet, Place du Docteur Baylac | Toulouse | Oui | 31300 | France |
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| ID | Term |
|---|---|
| D001932 | Brain Neoplasms |
| ID | Term |
|---|---|
| D016543 | Central Nervous System Neoplasms |
| D009423 | Nervous System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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The MRI images of patients in the Pre-End group will be analyzed. It will be possible to determine whether their tumors overlap in a specific area, which could indicate that this area is essential for the process being studied.
| one day after the inclusion |
| D001927 |
| Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |