Dexmedetomidine Nebulization for Attenuation of Pressor Response to Laryngoscopy and Endotracheal Intubation in Sever Preeclamptic Patients

Dexmedetomidine Nebulization for Attenuation of Pressor Response to Laryngoscopy and Endotracheal Intubation in Sever Preeclamptic Patients Undergoing Caesarean Section Under General Anaesthesia

Dexmedetomidine nebulization in sever preeclamptic patients

Dexmedetomidine nebulization for attenuation of pressor response to laryngoscopy and endotracheal intubation in sever preeclamptic patients undergoing caesarean section under general anaesthesia. A prospective randomized clinical trial.

Inclusion Criteria:

• Patients with severe pre-eclampsia scheduled for cesarean section under general anesthesia
• ASA II, III

Exclusion Criteria:

• sever obesity (BMI ≥ 40)
• Cardiac patients
• History of diabetes mellitus
• Renal dysfunction (elevated serum creatinine > 2mg\dl)
• hepatic dysfunction (elevated hepatic enzyme three times above normal)
• History to hypersensitivity to the tested drug.
• Emergency surgery
• Known fetal anomalies