Peripheral Nerve Activation Sensitivity

Peripheral Nerve Activation Sensitivity to Electromagnetic and Electrical Stimulation in the Upper Arm

Volunteers will undergo various peripheral nerve stimulations (electric, electromagnetic, and temporal interference) to evaluate each method's sensitivity. The main objective is to examine the relationship between nerve activation and coil placement relative to the nerve, as well as how different coil types influence maximal nerve activation.

Inclusion Criteria:

• Person aged > 18 years
• Signed informed consent
• Healthy
• Willingness and ability to adhere to study procedures

Exclusion Criteria:

• Known hypersensitivity to electric or electromagnetic stimulation
• Any implanted metal or electronic device in the upper body (except dental work such as fillings or braces), e.g., active medical devices, metal implants
• Neurological or neuromuscular disorders or conditions
• History of seizures or epilepsy
• Current treatment with drugs that lower seizure threshold (e.g., certain analgesics, methylxanthines, antipsychotics, antidepressants, antiepileptics, anesthetics)
• Pregnancy or breastfeeding
• Surgical intervention of the arm within the last 4 weeks
• Allergy to adhesives or ultrasound gel components (e.g., polyethylene glycols)
• Skin lesions, infections, or strictures in the arm region
• Tattoos on the stimulated (right) arm and hand, or in any area likely to be captured in video recordings
• Inability to follow study procedures (e.g., due to language barrier, psychological disorders, dementia)
• Participant deprived of liberty by administrative or judicial decision or under legal guardianship