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| Name | Class |
|---|---|
| Istanbul University - Cerrahpasa | OTHER |
| Saglik Bilimleri Universitesi | OTHER |
| Yeditepe University | OTHER |
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Acute decompensated heart failure (ADHF) is a severe condition characterized by rapid deterioration of cardiac function, leading to impaired oxygen delivery and multi-organ dysfunction. ADHF often results in reduced physical and respiratory capacity, greater dependence on oxygen support, difficulty performing daily activities, and prolonged hospital stays. In recent years, early exercise-based cardiopulmonary rehabilitation (CPR) has been introduced as part of heart failure management. Evidence suggests that early CPR improves overall health and cardiac function in heart failure patients. However, data regarding its effects in ADHF remain limited. While some studies indicate that early CPR enhances physical function, its impact on respiratory parameters and clinical outcomes is less well established.
Cardiopulmonary rehabilitation is a multidisciplinary program designed to promote physical, psychological, and social recovery in patients with cardiovascular and pulmonary diseases. It includes exercise training, education, psychosocial support, and behavioral strategies. Early CPR specifically aims to improve cardiovascular and respiratory functions in heart failure patients. Initiating CPR in the early phase of ADHF may accelerate recovery, strengthen cardiopulmonary function, shorten hospitalization, and improve quality of life.
This study aims to evaluate the effects of early CPR on functional capacity, hemodynamic parameters, and respiratory parameters in patients with ADHF.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Early cardiopulmonary rehabilitation group | Experimental | Exercise-based cardiopulmonary rehabilitation will be applied to this group during the hospital stay every day for 3 times a day. |
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| Control Group | Other | Routine in-hospital care will be applied to this group. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Early Cardiopulmonary Rehabilitation | Other | An individualized CPR program including positioning, deep breathing exercises (diaphragmatic and segmental breathing exercises), pursed-lip breathing exercises, breathing exercises using incentive spirometry, and progressive mobilization exercises (in-bed range of motion exercises, sitting, standing, and walking exercises) |
| Measure | Description | Time Frame |
|---|---|---|
| Functional capacity | It will be evaluated using 6-min walk test according to the guideline of American Thoracic Society | At baseline and at hospital discharge, up to 14 days after admission |
| Physical performance | It will evaluated using Short Physical Performance Battery. | At baseline and at hospital discharge, up to 14 days after admission |
| Measure | Description | Time Frame |
|---|---|---|
| Maximum inspiratory and expiratory capacity | It will be evaluated using incentive spirometer. | At baseline and at hospital discharge, up to 14 days after admission |
| Hemodynamic responses to exercise |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul University- Cerrahpasa, Cardiology Institute | Istanbul | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| Routine in-hospital care | Other | Routine in-hospital care for acute decompansated heart failure |
|
The change in heart rate before and after exercise will be recorded
| At baseline and at hospital discharge, up to 14 days after admission |
| Hemodynamic responses to exercise | The change in blood pressure before and after exercise will be recorded | At baseline and at hospital discharge, up to 14 days after admission |
| Hemodynamic responses to exercise | The change in oxygen saturation before and after exercise will be recorded | At baseline and at hospital discharge, up to 14 days after admission |
| Subjective symptom responses to exercise | Subjective symptom responses to exercise will be evaluated by determining changes in the Modified Borg Dyspnea and Fatigue scales before and after exercise. | At baseline and at hospital discharge, up to 14 days after admission |