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Fungal vascular graft and endograft infections (VGEIs) are rare but life-threatening infections. Best therapeutic management is unknown. This study retrospectively gathers fungal VGEIs from 12 university hospital centers in France over a 10 year's period in order to describe their epidemiology, clinical features, therapeutic management and outcomes. Focusing on Candida spp. VGEIs, we aim to determine prognosis factors associated with therapeutic management
Fungal vascular graft and endograft infections (VGEIs) are rare but life-threatening infections. Candida spp. is the most frequent fungal agent. Main risk factor is prostheto-digestive fistula. Best therapeutic management is unknown. The aim of FUNGIVAS study is to describe epidemiology, clinical features, therapeutic management and outcomes of fungal VGEIs and determine prognosis factors associated with therapeutic management. This study retrospectively gathers fungal VGEIs from 12 university hospital centers in France from January 2013 to January 2023. Patients will be identified from mycology laboratories that have diagnosed the fungal infection on a vascular sample. Demographic, clinical, biological, imaging and outcome data will be collected using a secure and anonymous questionnaire
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| epidemiology and medical treatment strategies | Other | Analysis of the epidemiology and medical and surgical treatment strategies for fungal IPEV in France between January 2013 and January 2023 |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of mortality | Rate of all-cause mortality | Year 1 |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of mortality | Rate of all-cause mortality | Month 1 |
| Fungal vascular graft and endograft infections-related mortality | Fungal vascular graft and endograft infections-related mortality |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with fungal infection on a vascular sample
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mathilde Puges, MD | Contact | +335 56 79 55 36 | mathilde.puges@u-bordeaux.fr | |
| Carole Vignals, MD | Contact | +335 56 79 55 36 | carole.vignals@aphp.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Bordeaux | Bordeaux | France |
|
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| ID | Term |
|---|---|
| D009181 | Mycoses |
| C536972 | Torulopsis |
| ID | Term |
|---|---|
| D001423 | Bacterial Infections and Mycoses |
| D007239 | Infections |
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| Month 1, Year 1 |
| Rate of cure | Rate of cure, defined as : alive and without therapeutic failure (non-control of infection requiring repeat surgery or modification of anti-infective treatment) | Year 1 |
| Rate of sequelae | Rate of sequelae | Year 1 |