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The purpose of this study is to find out which type of wound closure after emergency abdominal surgery leads to fewer wound infections and better recovery: closing the wound immediately after surgery (called primary closure) or waiting a few days before closing the skin (called delayed primary closure).
Wound infection is a common problem after emergency abdominal surgery (also called laparotomy). Some surgeons close the skin right away, while others wait a few days to reduce the risk of infection.
This study will help find out which method is better.
The main questions the study aims to answer are:
In this clinical trial:
The results will help doctors choose the safest and most effective way to close surgical wounds after emergency abdominal surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Primary Closure | Active Comparator | Skin closed immediately after laparotomy |
|
| Delayed Primary Closure | Experimental | Skin closed 3 - 5 days after laparotomy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Immediate skin closure | Procedure | After laparotomy wounds will be closed primarily using no. 1 vicryl suture |
|
| Measure | Description | Time Frame |
|---|---|---|
| Wound Infection | Surgical Site infection - Presence any features of erythema, pain, pus discharge on examination of surgical wound and new onset fever (> 98.6 F) | From date of surgery to Four weeks postoperatively |
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| Measure | Description | Time Frame |
|---|---|---|
| Hospital Stay | Duration of stay (days) in hospital after laparotomy | From date of surgery until date of hospital discharge, up to 28 days |
| Wound dehiscence | A partial or total separation of previously approximated wound edges |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Amjad A Professor, FRCS | Bakhtawar Amin Medical and Dental College | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Bakhtawar Amin Medical and Dental College | Multan | Punjab Province | 60000 | Pakistan |
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| Delayed primary closure | Procedure | Deeper layers of wound will be closed after surgery and loose mattress sutures will be applied to skin with prolene. After three to five days of daily dressing with bactericidal solution, the skin will be closed |
|
| From date of laparotomy to Four weeks post-operatively |
| ID | Term |
|---|---|
| D014946 | Wound Infection |
| ID | Term |
|---|---|
| D007239 | Infections |
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