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| ID | Type | Description | Link |
|---|---|---|---|
| SCHW 2023/2-1 | Other Grant/Funding Number | German Research Foundation |
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| Name | Class |
|---|---|
| University of Twente | OTHER |
| University of Oxford | OTHER |
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The investigators aim to test an interface to phase-lock transcranial alternating current stimulation (tACS) and deep brain stimulation (DBS) for future studies investigating the effects of different time-lags between DBS and tACS on the behavioural and neural level. To test if the interface works in patients with DBS, the investigators record EEG during synchronized tACS-DBS in several patients. The investigators hypothesize that they can apply tACS at the desired phase-lags relative to DBS pulses and confirm this with EEG measurements of the DBS and tACS artifact.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| phase-lags | Experimental | Device: phase-lags
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DBS-coupled tACS | Device | tACS will be applied in a phase-coupled manner, so that tACS and DBS are synchronized |
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| Measure | Description | Time Frame |
|---|---|---|
| Phase-locking success (delay to intended phase) | The investigators will measure the temporal precision of the locking of the tACS to the DBS pulses should be seen. To this end, the tACS-DBS artifact and the triggers given from the interface device will be analysed offline in MATLAB. | during stimulation procedure |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Bettina C. Schwab, PhD | UKE Hamburg | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Medical Center Hamburg-Eppendorf | Hamburg | 20246 | Germany |
not compatible with ethics protocol
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Active DBS and active tACS with different phase-lags (at least 4: 0°, 90°, 180°, 270°)
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