Target Planning for Placement of DBS-electrodes and Follow-up of the Clinical Efficacy of Stimulation

Target Planning for Placement of DBS-electrodes and Follow-up of the Clinical Efficacy of Stimulation

Deep brain stimulation (DBS) has been established as therapy for severe forms of Parkinson's disease and other indications. A common target for stimulation is the subthalamic nucleus (STN). Nevertheless, there is no agreement on the mechanisms how DBS leads to clinical improvement.

The project aims to describe the variability of target coordinates in the patient group and to relate it to clinical outcome as documented in standardized questionaires.

• Trial with surgical intervention

Deep brain stimulation (DBS) has been established as therapy for severe forms of Parkinson's disease and other indications. A common target for stimulation is the subthalamic nucleus (STN). Nevertheless, there is no agreement on the mechanisms how DBS leads to clinical improvement.

The project aims to describe the variability of target coordinates in the patient group and to relate it to clinical outcome as documented in standardized questionaires.

Inclusion criteria:

• Patients fullfill all criteria for implantation of deep brain stimulation (DBS) electrodes
• Patients are able to give informed written consent

Exclusion criteria:

• Patients do not their give informed written consent