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| Name | Class |
|---|---|
| Yuebei People's Hospital | OTHER |
| People's Hospital of Xinjiang Uygur Autonomous Region | OTHER |
| Gansu Provincial Hospital | OTHER |
| Shenzhen Center for Chronic Disease Control |
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The goal of this observational study is to observe the characteristics of cardiopulmonary exercise testing (CPET) parameters in patients across different cardiovascular diseases and to evaluate the predictive value of multiparameter cardiopulmonary indices for 5-year major adverse cardiovascular events (MACE).
To investigate the CPET characteristics in patients with various cardiovascular diseases (including acute myocardial infarction, heart failure, cardiomyopathy, valvular heart disease, coronary artery disease, and perioperative cardiac surgery), with annual follow-up of major adverse cardiovascular events (MACE) for five years, and to establish the predictive value of combined CPET parameters for MACE in this population
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| cardiovascular disease patient with MACE | cardiovascular disease patient with MACE（Cardiac death, unplanned revascularization, cardiac readmission, non-fatal myocardial infarction, and stroke） | ||
| cardiovascular disease patient without MACE |
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| Measure | Description | Time Frame |
|---|---|---|
| Characteristics of CPET parameters across different cardiovascular diseases. | Cardiopulmonary exercise testing (CPET) was performed using exercise cardiopulmonary testing systems from VYAIRE (Germany) and SCHILLER (Switzerland). A symptom-limited maximal exercise test with a 1-minute ramp incremental protocol (Ramp protocol) was adopted, designed to complete the workload test within 8-12 minutes according to the incremental power calculation formula. The incremental workload was calculated as follows: Unloaded VO₂ (ml/min) per minute = 150 + (6 × body weight) Predicted peak VO₂max (ml/min) per minute for males = (height in cm - age in years) × 20 Predicted peak VO₂max (ml/min) per minute for females = (height in cm - age in years) × 14 Incremental power per minute = (predicted peak VO₂max - unloaded VO₂)/100 During exercise, real-time cardiopulmonary parameters were collected, including peak oxygen uptake (VO₂peak), anaerobic threshold (AT), maximal cycling workload, respiratory rate, minute ventilation (VE), and ventilatory efficiency, among others. | After enrollment |
| Incidence of 5-year MACE | MACE (cardiovascular death, unplanned repeat revascularization, cardiac rehospitalization, non-fatal myocardial infarction, stroke) | from enrollment to 5 years post-enrollment |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of individual events of MACE per year (incidence of cardiac death, unplanned rereconstitution, cardiac rehospitalization, nonfatal myocardial infarction, and stroke) | yearly for 5 years (Year 1/2/3/4/5 from enrollment) |
| Measure | Description | Time Frame |
|---|---|---|
| Incidence rate of adverse events during exercise | During each exercise session and within 24 hours after exercise |
Inclusion Criteria:
Exclusion Criteria:
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China CardioVascular Disease Patient and healthy control group
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Guangdong Provincial People's Hospital | Guangzhou | Guangdong | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 10027821 | Result | Shephard RJ, Balady GJ. Exercise as cardiovascular therapy. Circulation. 1999 Feb 23;99(7):963-72. doi: 10.1161/01.cir.99.7.963. No abstract available. | |
| 30115967 | Result | Fiuza-Luces C, Santos-Lozano A, Joyner M, Carrera-Bastos P, Picazo O, Zugaza JL, Izquierdo M, Ruilope LM, Lucia A. Exercise benefits in cardiovascular disease: beyond attenuation of traditional risk factors. Nat Rev Cardiol. 2018 Dec;15(12):731-743. doi: 10.1038/s41569-018-0065-1. |
| Label | URL |
|---|---|
| websites associated with the cited references | View source |
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| OTHER |
| Guangdong Provincial Hospital of Traditional Chinese Medicine | OTHER |
| Nanfang Hospital, Southern Medical University | OTHER |
| Third Affiliated Hospital, Sun Yat-Sen University | OTHER |
| Zhongshan Hospital Of Traditional Chinese Medicine | OTHER |
| Zhengzhou Central Hospital | OTHER |
| Dongguan Binhaiwan Central Hospital | UNKNOWN |
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| 31891317 | Result | DeCato TW, Haverkamp H, Hegewald MJ. Cardiopulmonary Exercise Testing (CPET). Am J Respir Crit Care Med. 2020 Jan 1;201(1):P1-P2. doi: 10.1164/rccm.2011P1. No abstract available. |
| ID | Term |
|---|---|
| D003643 | Death |
| D020521 | Stroke |
| D002318 | Cardiovascular Diseases |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
| D014652 | Vascular Diseases |
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