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The goal of this study is to understand how menopause affects skin aging in Egyptian women between the ages of 40 and 60.
The main question the study wants to answer is:
Does menopause cause any changes in how the skin ages?
To find out, the participants will be divided into two groups based on their menstrual history:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Dermoscopy | Device | dermoscopic assessment of skin aging signs |
| Measure | Description | Time Frame |
|---|---|---|
| Clinical skin aging severity using Glogau Photoaging Scale | The Glogau Photoaging Scale will be used for evaluation. Facial assessment will be conducted both at rest and during facial animation to observe dynamic changes. Participant will be categorized into 4 types or grades where type 1 is mild skin aging and type 4 is severe skin aging | Assessed once at baseline during participant's visit |
| Dermoscopic skin aging score using the dermoscopic photoaging assessment scale | this scale is used to assess facial skin aging. The face will be divided into four regions: the forehead, right cheek, left cheek, and chin. Each region will be examined for the presence of the following features: yellowish discoloration, yellow papules, white linear areas indicating skin atrophy, lentigines, hypo- or hyperpigmented macules, telangiectasia, actinic keratoses, senile comedones, deep wrinkles, superficial wrinkles, and criss-cross wrinkles. Scoring follows a binary (yes/no) approach, where the presence of a given feature in any of the four regions scores one point, yielding a total possible score ranging from 0 to 44. a higher score means worse outcome. | Assessed once at baseline during participant 's visit |
| Measure | Description | Time Frame |
|---|---|---|
| Prevalence of specific clinical and dermoscopic aging features | Recorded during clinical and dermoscopic assessment at baseline | |
| Correlation between menopausal status and severity of skin aging | Assessed once at baseline during participant's visit based on menopausal history and skin aging scores |
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Inclusion Criteria:
Females aged 40 to 60 years
Egyptian nationality or residency
Ability to provide informed consent
Classified as either:
Exclusion Criteria:
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This study will include Egyptian women between the ages of 40 and 60 years who are either premenopausal or postmenopausal, based on their menstrual history.
participants must be in good general health and not currently receiving hormone replacement therapy or any treatment known to affect skin condition.
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| ID | Term |
|---|---|
| D046169 | Dermoscopy |
| ID | Term |
|---|---|
| D000069416 | Intravital Microscopy |
| D008853 | Microscopy |
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
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| Correlation between menopausal duration and skin aging | Menopausal duration collected via history at baseline; skin aging assessed at baseline |
| D003933 | Diagnosis |
| D008919 | Investigative Techniques |