Menopause and Oral Health | NCT05513118 | Trialant

Menopause and Oral Health | NCT05513118 | Trialant

Sponsor/Collaborators Module

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
Post-menopausal women			Diagnostic Test: Periodontal clinical examination and gingival crevicular fluid, saliva, dental plaque, serum sampling
Regularly mensturating women			Diagnostic Test: Periodontal clinical examination and gingival crevicular fluid, saliva, dental plaque, serum sampling

Interventions

Name	Type	Description	Arm Group Labels	Other Names
Periodontal clinical examination and gingival crevicular fluid, saliva, dental plaque, serum sampling	Diagnostic Test	Probing pocket depth was defined as the distance in millimeters from the gingival margin to the base of the gingival sulcus measured using a manual probe (Michigan 0 probe with Williams Markings) in all the teeth present except for third molars. Similarly, clinical attachment level (CAL) was measured as distance from cementoenamel junction to the base of pocket and recorded manually to the nearest millimeter marking on probe. 1 mililiter of saliva was obtained by each participant. Subgingival dental plaque was collected with sterile endodontic paperpoints from mesial sides of each natural teeth without a prostethic restoration. Gingival crevicular fluid samples were collected with absorbent paper strips. Serum samples were also collected at the time of visit.

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
Periodontitis	Interdental attachment loss is detectable at ≥2 non-adjacent teeth, or buccal/oral attachment loss ≥3 mm with pocketing >3 mm at ≥2 adjacent teeth were present.	1 month