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The study aim will be to assess the prognostic impact and value of central venous oxygen saturation on post arrest patients.
Central venous oxygen saturation (ScvOâ‚‚) is a very important measurement which can be easily taken in a critical care environment by both medical and nursing staff. It provides an understanding of the patient's oxygen delivery, oxygen consumption and cardiac output. It has a key role within early goal-directed therapy and has been shown to decrease mortality when taken and analysed appropriately. (Central venous oxygen saturation: analysis, clinical use and effects on mortality,2013) Venous oxygen saturation (SvO2) measures the blood's oxygen content returning to the right side of the heart after perfusing the entire body. When the oxygen supply is insufficient to meet the metabolic demands of the tissues, an abnormal SvO2 ensues and reflects an inadequacy in systemic oxygenation. SvO2 is, therefore, dependent on oxygen delivery and oxygen extraction. Venous oximetry is used in specific clinical settings of hemodynamic instability, such as in critical illnesses, perioperative periods of major surgeries, heart failure, sepsis andd post arrest patients. The venous blood in the pulmonary artery represents oxygen extraction in the whole body and is called mixed venous oxygen saturation (SmvO2). It was measured using a pulmonary artery catheter (PAC). A second, less invasive method of measuring SvO2 is via a central venous catheter (CVC) positioned in the superior vena cava and is called the central venous oxygen saturation (ScvO2).
Central venous oxygen saturation (ScvO(2)) is suggested to reflect the adequacy of oxygen delivery, and the main objective of the present study was to determine whether ScvO(2) is associated with outcome in haemodynamically stabilized post arrest patients predicting mortality and outcome based on central venous oxygen saturation
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| Measure | Description | Time Frame |
|---|---|---|
| central venous oxygen saturation impact on prognosis of post arrest patients | evaluating prognostic impact of oxygen saturation extracted from a central venous line blood sample on post arrest patients sample from (internal jagular vein) more or less than 50% oxygen saturation on prognosis of post arrest patients and recurrent arrests and overall improvement and time of expected and full recovery | time of follow up expected from time of successful ROSC until full improvement or recurrent arrest and death From date of cardiac arrest until date of first documented improvement or date of death due to any cause whichever came first assessed up in 2 mo |
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Inclusion Criteria:
Exclusion Criteria:
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post arrest patients in assiut university hospital both genders above 16 years old
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Assiut university | Asyut | Egypt |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22369912 | Background | Gallet R, Lellouche N, Mitchell-Heggs L, Bouhemad B, Bensaid A, Dubois-Rande JL, Gueret P, Lim P. Prognosis value of central venous oxygen saturation in acute decompensated heart failure. Arch Cardiovasc Dis. 2012 Jan;105(1):5-12. doi: 10.1016/j.acvd.2011.10.005. Epub 2012 Jan 13. | |
| 37891623 | Background | Grand J, Hassager C, Schmidt H, Molstrom S, Nyholm B, Hoigaard HF, Dahl JS, Meyer M, Beske RP, Obling L, Kjaergaard J, Moller JE. Serial assessments of cardiac output and mixed venous oxygen saturation in comatose patients after out-of-hospital cardiac arrest. Crit Care. 2023 Oct 27;27(1):410. doi: 10.1186/s13054-023-04704-2. |
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central venous blood samples
| 37292584 | Background | Rodriguez-Scarpetta MA, Sepulveda-Tobon AM, Daza-Arana JE, Lozada-Ramos H, Alzate-Sanchez RA. Central Oxygen Venous Saturation and Mortality in Patients Undergoing Coronary Artery Bypass Grafting. Ther Clin Risk Manag. 2023 Jun 3;19:447-454. doi: 10.2147/TCRM.S407454. eCollection 2023. |