Effect of Vitamin-D as an Adjuvant to Phototherapy in Reduction of Indirect Serum Bilirubin

Determination of the Effect of Vitamin-D as an Adjuvant to Phototherapy in Reduction of Indirect Serum Bilirubin Among Neonates With Exaggerated Physiological Hyperbilirubinemia.

The study aimed at filling the gaps by evaluating the effectiveness of vitamin-D as an adjuvant to phototherapy in reduction of indirect serum bilirubin among neonates with exaggerated physiological hyperbilirubinemia.

If vitamin-D has been found effective as an adjuvant to phototherapy in the treatment of exaggerated physiological hyperbilirubinemia, it may help to reduce the serum bilirubin level rapidly. It may also reduce the complications by shortening the duration of phototherapy to offer better patient compliance and better patient outcomes.

Inclusion Criteria:

• Newborns of any gender
• Age of 3rd day of life to 8th day of life
• Gestation age ≥37 to ≤42 weeks
• Total serum bilirubin level more than 12.9 mg/dL
• Weight > 2.5 kg

Exclusion Criteria:

• Congenital defects (on physical examination)
• Large for gestational age infant
• Rh Incompatibility (were excluded on basis of blood grouping of mother and baby)
• ABO Incompatibility (were excluded on basis of blood grouping of mother and baby)
• Neonatal sepsis