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Neonatal jaundice frequently occur during initial week of life. Neonatal jaundice is one of the leading causes of hospital admission and readmission. Some studies have suggested that the healthy newborns with hyperbilirubinemia outside the physiological range have notably reduced serum vitamin D levels. This deficiency is inversely associated with neonatal hyperbilirubinemia, suggesting that low vitamin D levels could be a potential risk factor for jaundice among neonates.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group-A | Experimental | Neonates receive phototherapy plus vitamin D |
|
| Group-B | No Intervention | Neonates will receive only phototherapy |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vitamin D | Drug | Vitamin D supplementation as vitamin D, 2 drops i.e., 800 IU daily for 5 days. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Total Serum bilirubin levels | Total Serum bilirubin levels evaluated | 5 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Zeeshan Afzal, FCPS | Pediatric Medicine Department University of Child Health Sciences, Children's Hospital Lahore | Principal Investigator |
| Wajiha Rizwan, FCPS | Pediatric Medicine Department University of Child Health Sciences, Children's Hospital Lahore | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pediatric Medicine Department University of Child Health Sciences, Children's Hospital Lahore | Lahore | Pakistan |
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| ID | Term |
|---|---|
| D007567 | Jaundice, Neonatal |
| ID | Term |
|---|---|
| D051556 | Hyperbilirubinemia, Neonatal |
| D007232 | Infant, Newborn, Diseases |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D006932 | Hyperbilirubinemia |
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| ID | Term |
|---|---|
| D014807 | Vitamin D |
| ID | Term |
|---|---|
| D012632 | Secosteroids |
| D013256 | Steroids |
| D000072473 | Fused-Ring Compounds |
| D011083 | Polycyclic Compounds |
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Randomized controlled trial
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| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |