Effect of Remifentanil on Pruritus and Paresthesia of Fospropofol Disodium Anesthesia

Effect of Remifentanil on Pruritus and Paresthesia Caused by Fospropofol Disodium Anesthesia

Explore the effect of remifentanil on pruritus and paresthesia induced by fospropofol disodium in adults

Explore the effect of remifentanil on pruritus and paresthesia caused by fospropofol disodium in adults, to observe the manifestations and duration of pruritus and paresthesia

Inclusion Criteria:

• Age 18-80 years old, plans to undergo elective non-cardiac surgery under general anesthesia.
• ASA I-II;
• The operation duration > 30 min;
• BMI 18-30kg /m2；
• Sign the informed consent form.

Exclusion Criteria:

• history of drug abuse or alcohol dependence;
• used sedative or analgesic drugs before operation;
• with severe liver and kidney function impairment;
• allergic to propofol and lipids;
• surgery that directly affect hemodynamics with surgical operations, such as macrovascular surgery;
• abnormal coagulation function, endocrine diseases or other effects on hemodynamic status;
• Participation in other clinical researchers in the past 3 months