Effect OF Lactase Enzyme Supplements ON Intolerance IN Preterm Neonates

Effect OF Lactase Enzyme Supplements ON Protection Against Feeding Intolerance IN Preterm Neonates

This study aims to study the effect of lactase enzyme in preventing feeding intolerance in preterm neonates in neonatal intensive care unit at Alexandria University Children's Hospital.

Inclusion criteria will be as follows:

• Preterm neonates ≤ 32 weeks gestational age.
• Start feeding in the first 72 hours of life. 8. Exclusion criteria

Patients with any of the following will be excluded:

1. Parental consent lacking/refusal.
2. Obvious major congenital abnormalities.
3. Infants more than 72 hours of age at the time of randomization.
4. Delayed introduction of feeding (beyond three days of life).
5. Known galactosemia.
6. Severe IUGR. -