Safety and Efficacy of Oral Bovine Lactoferrin

Effectivness and Safety of Oral Bovine Lactoferrin in Neonatal Sepsis and Necrotizing Enterocolitis and Its Effect on Anaemia of Prematurity

Oral lactoferrin versus Placebo will be given to preterm neonates

200 patient were included in the study , one hundred received oral placebo in the form of 2 ml saline , the other 100 preterm neonates received oral lactoferrin with monitoring of C-reactive protein , different cultures, complete blood count on day 7 and after one month.

Inclusion Criteria:

All neonates born at Cairo university hospital NICU

Exclusion Criteria:

• Neonatal deaths before 3 days postnatal .
• Neonates with underlying gastrointestinal problems that prevent oral intake.
• Neonates with major congenital anomalies .
• Neonates with severe hypoxic ischemic encephaloapathy .
• Neonates whose parents refuse to participate.