Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Title: Comparing Two Methods of Topical Anesthesia for Fiberoptic Bronchoscopy
Purpose: To compare the effectiveness of two methods of anesthesia, pre-procedure lignocaine spray (PPL) and spray-as-you-go (SAYG), in reducing discomfort and improving operator comfort during fiberoptic bronchoscopy.
Study Design: Randomized controlled trial Participants: 50 patients undergoing fiberoptic bronchoscopy Interventions: Patients received either PPL or SAYG anesthesia
Outcomes:
Results:
Implications: Both PPL and SAYG methods can be effectively used for fiberoptic bronchoscopy, with potential implications for procedural efficiency and patient outcomes.
A single-blind RCT included 50 participants were randomly assigned to two groups (n = 25 each). Standard procedural sedation with midazolam and 2 mL of 4% lignocaine spray in the oropharynx was used to suppress the gag reflex. Additionally, 2% lignocaine spray was administered during the procedure according to body weight (3 mg/kg) via oral scope insertion. Cough severity, pain perception, and operator comfort were assessed using the Visual Analogue Scale, Faces Pain Rating Scale, and a 4-point Likert scale, respectively.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pre-procedure lignocaine spray (PPL) | Active Comparator | Participants received:
|
|
| Spray-as-you-go (SAYG) Airway Anesthesia | Active Comparator | Participants received:
|
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pre-procedure lignocaine spray (PPL) | Drug | Administration of 2 mL of 4% lignocaine spray in the oropharynx before the fiberoptic bronchoscopy procedure, followed by additional 2% lignocaine spray according to body weight (3 mg/kg) |
| Measure | Description | Time Frame |
|---|---|---|
| Patient discomfort and operator comfort during fiberoptic bronchoscopy | This composite outcome evaluates three distinct parameters:
All measures will be analyzed separately to compare PPL and SAYG techniques | One year |
| Visual Analogue Scale | Cough severity measured using 100-mm Visual Analog Scale where 0 mm = no cough and 100 mm = worst cough imaginable. Higher scores indicate worse cough severity. | One year |
| Faces Pain Rating Scale | Pain intensity measured using Faces Pain Rating Scale (0-10) where 0 = no pain and 10 = worst pain possible. Higher scores indicate worse pain. | One year |
| 4-point Likert scale | Operator comfort assessed via 4-point Likert scale where 1 = Not comfortable, 2 = Slightly uncomfortable, 3 = Comfortable, and 4 = Very comfortable. Higher scores indicate better comfort. | One year |
| Measure | Description | Time Frame |
|---|---|---|
| Procedure duration | Comparison of procedure duration between PPL and SAYG airway anesthesia methods, measured in minutes from scope insertion to withdrawal. | One year |
| Measure | Description | Time Frame |
|---|---|---|
| Comparative effectiveness of PPL versus SAYG anesthesia in cough suppression using the Visual Analog Scale (VAS) | This study will compare the effectiveness of pre-procedure lignocaine spray (PPL) and spray-as-you-go (SAYG) techniques in suppressing cough, measured by the Visual Analog Scale (VAS). The VAS is a 100-mm scale where 0 = no cough and 100 = worst cough, with higher scores indicating worse outcomes. |
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Talha Mahmud, PhD | Shaikh Zayed Medical Complex, Federal Postgraduate Medical Institute, Lahore Pakistan. | Principal Investigator |
| Hira Ishtiaq, MD | Shaikh Zayed Medical Complex, Federal Postgraduate Medical Institute, Lahore Pakistan. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shaikh Zayed Hospital, Federal Postgraduate Medical Institute | Lahore | Punjab Province | 54000 | Pakistan |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
A single-blind randomized controlled trial was conducted at the Pulmonology Department of Shaikh Zayed Hospital, Lahore, Pakistan, from March 2021 to March 2022.
Not provided
Not provided
Not provided
Not provided
| Lignocaine Spray (Spray-as-you-go) | Drug | Administration of 2% lignocaine spray via oral scope insertion during the fiberoptic bronchoscopy procedure, according to body weight (3 mg/kg), with standard procedural sedation with midazolam and initial 2 mL of 4% lignocaine spray in the oropharynx for gag reflex suppression |
|
| One year |
| Comparative effectiveness of PPL versus SAYG anesthesia in pain control using the Faces Pain Rating Scale (FPRS) | This study will compare the effectiveness of PPL and SAYG techniques in pain control, assessed via the Faces Pain Rating Scale (FPRS). The FPRS is a 0-10 scale where 0 = no pain and 10 = worst pain, with higher scores indicating worse outcomes. | One year |
| Comparative effectiveness of PPL versus SAYG anesthesia in operator comfort using the Operator Likert Scale | This study will compare the effectiveness of PPL and SAYG techniques in operator comfort, evaluated using a 4-point Likert scale (1 = Not comfortable, 4 = Very comfortable), with higher scores indicating better outcomes. | One year |
| ID | Term |
|---|---|
| D014133 | Tracheal Diseases |
| ID | Term |
|---|---|
| D012140 | Respiratory Tract Diseases |
Not provided
Not provided