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optimal time to liberate from mechanical ventilation is highly prioritized since improper extubation time lead to serious consequences
Several parameters were proposed to assess proper weaning time including diaphragmatic ultrasound and extra-diaghragmatic muscles. previous research concluded an ability of parasternal intercostal (PIC) thickening to predict weaning outcomes. researchers of current study assumed that temporal changes in PIC thickening would provide greater ability to predict weaning outcomes
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Parasternal intercostal thickening | Device | Temporal change in parasternal intercostal thickening fraction at initiation and 30 minutes of spontaneous breathing trial |
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy of change in PIC-TF in predicting successful weaning from mechanical ventilation | percentage of change in PIC TF in predicting weaning outcome (PIC TF30-PIC TF0) | At baseline and 30 minutes after initiation of spontaneous breathing trial |
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy of change in PIC-TF to predict reintubation | percentage of change in PIC TF at start and end of spontaneous breathing trial (PIC TF30-PIC TF0) | At baseline and 30 minutes after initiation of spontaneous breathing trial |
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Inclusion Criteria:
- Mechanically ventilated for 24 hours or more ready for weaning
Exclusion Criteria:
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Adult patient who are mechanically ventilated for 24 hours or more and ready for weaning
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University | Cairo | Cairo Governorate | 6890 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39174907 | Result | Helmy MA, Hasanin A, Milad LM, Mostafa M, Hamimy WI, Muhareb RS, Raafat H. Ability of parasternal intercostal muscle thickening fraction to predict reintubation in surgical patients with sepsis. BMC Anesthesiol. 2024 Aug 22;24(1):294. doi: 10.1186/s12871-024-02666-8. | |
| 36961635 | Result | Helmy MA, Milad LM, Hasanin AM, Mostafa M, Mannaa AH, Youssef MM, Abdelaziz M, Alkonaiesy R, Elshal MM, Hosny O. Parasternal intercostal thickening at hospital admission: a promising indicator for mechanical ventilation risk in subjects with severe COVID-19. J Clin Monit Comput. 2023 Oct;37(5):1287-1293. doi: 10.1007/s10877-023-00989-4. Epub 2023 Mar 24. |
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IPD may not be shared due to confidentiality, legal constraints, or the need to protect intellectual property rights.
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| 35487407 | Result | Helmy MA, Hasanin A, Milad LM, Mostafa M, Fathy S. Parasternal intercostal muscle thickening as a predictor of non-invasive ventilation failure in patients with COVID-19. Anaesth Crit Care Pain Med. 2022 Jun;41(3):101063. doi: 10.1016/j.accpm.2022.101063. Epub 2022 Apr 26. No abstract available. |
| 33940248 | Result | Helmy MA, Magdy Milad L, Osman SH, Ali MA, Hasanin A. Diaphragmatic excursion: A possible key player for predicting successful weaning in patients with severe COVID-19. Anaesth Crit Care Pain Med. 2021 Jun;40(3):100875. doi: 10.1016/j.accpm.2021.100875. Epub 2021 Apr 30. No abstract available. |
| 34748940 | Result | Adolf Helmy M, Magdy Milad L, Hasanin A, Mostafa M. The novel use of diaphragmatic excursion on hospital admission to predict the need for ventilatory support in patients with coronavirus disease 2019. Anaesth Crit Care Pain Med. 2021 Dec;40(6):100976. doi: 10.1016/j.accpm.2021.100976. Epub 2021 Nov 5. |