Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Shanghai Jiao Tong University School of Medicine | OTHER |
| Tianjin Eye Hospital | OTHER |
Not provided
Not provided
Not provided
Not provided
Not provided
The goal of this observational study is to investigate the clinical features of congenital ptosis in children by analyzing eyelid movement captured through smartphone videos. The main question it aims to answer is:
Can video-based eyelid measurements and levator muscle function grading provide useful guidance for the treatment of congenital ptosis in children?
Participants are children diagnosed with congenital ptosis. Their blinking behavior will be recorded using a smartphone, and eyelid morphology and muscle strength will be assessed from the video data.
In this study, we developed a two-module system for the evaluation of congenital ptosis in children based on smartphone video recordings. The first module performs morphological measurements of eyelid parameters (e.g., palpebral fissure height, margin reflex distance) extracted from blink videos. The accuracy of this module was assessed through agreement analysis between automated measurements and manual measurements performed by clinicians.
The second module focuses on levator function grading. The automated grading results were compared against clinical assessments by senior oculoplastic specialists, which served as the gold standard, to evaluate the model's accuracy. Additionally, we compared the model's performance to that of junior ophthalmology residents to assess the system's clinical assistive value in real-world scenarios.
Based on these modules, we developed a smartphone-based application for remote ptosis assessment. A multi-center clinical validation study was designed to evaluate the feasibility, consistency, and generalizability of the system in different clinical settings.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| congenital ptosis |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ptosis | Other | no intervention |
|
| Measure | Description | Time Frame |
|---|---|---|
| levator function testing | One-time assessment; results available within 1 week of data collection. |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Inclusion criteria required participants aged ≤18 years with compliance during video recording. Congenital ptosis diagnosis mandated documented symptom onset within the first year of life and bilateral or unilateral MRD1 of < 2.5 mm. Healthy controls exhibited age-appropriate ocular development without eyelid abnormalities.
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| 2 nd Affiliated Hospital, School of Medicine, Zhejiang University, China | Hangzhou | Zhejiang | 310009 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41844953 | Derived | Li H, Cao J, Duan S, Hu S, Lou L, Lin M, Jian T, Shao J, Zhang X, Chen P, He Y, Wang J, Huang S, Ye J. From blink to care: smartphone video-based functional analysis and personalized management in pediatric blepharoptosis. NPJ Digit Med. 2026 Mar 18;9(1):358. doi: 10.1038/s41746-026-02510-y. |
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| C415582 | BPESC1 lncRNA, human |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided