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This study plans to assess eyelid topology (such as margin reflex distance, eyelid contour, and corneal exposure area) and blinking (such as frequency, velocity, and duration), using deep learning method to automatically extract eyelid topological features, and to predict subtypes of levator function, using deep learning method to extract blinking features, in order to provide new ideas and means to assess eyelid topology and kinetics.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Normal participants |
| ||
| Patients with blepharoptosis |
| ||
| Patients with blepharospasm |
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| Patients with dry eye disease |
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| Patients with Graves' disease |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Photography | Other | Facial photographs and blinking videos are taken |
|
| Measure | Description | Time Frame |
|---|---|---|
| one-dimensional parameters of eyelid topology | Palpebral fissure length [Margin reflex distance 1, Margin reflex distance 2], Lid length [Upper lid length, Lower lid length], Multiple mid-pupil lid distances | through study completion, 5 years |
| two-dimensional parameters of eyelid topology | Palpebral fissure area [Medial area, Corneal area, Lateral area] | through study completion, 5 years |
| subtypes of levator function | Levator function is classified into three categories: good, fair and poor | through study completion, 5 years |
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Inclusion Criteria:
Exclusion Criteria:
variable ptosis (e.g., myasthenia gravis), entropion, ectropion, enophthalmos, exophthalmos, strabismus, and abnormalities of pupil
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100 normal volunteers without eyelid diseases 100 patients with blepharoptosis 100 patients with blepharospasm 100 patients with dry eye disease 100 patients with Graves' disease
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Juan Ye | Contact | +86-571-87783897 | yejuan@zju.edu.cn | |
| Lixia Lou | Contact | +86-15088681589 | loulixia110@zju.edu.cn |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Juan Ye | Recruiting | Hangzhou | Zhejiang | 310000 | China |
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| ID | Term |
|---|---|
| D005141 | Eyelid Diseases |
| ID | Term |
|---|---|
| D005128 | Eye Diseases |
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| ID | Term |
|---|---|
| D010781 | Photography |
| ID | Term |
|---|---|
| D003952 | Diagnostic Imaging |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D008919 | Investigative Techniques |
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