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The objective of this observational study was to understand the healing of corneal incision after cataract surgery in diabetic patients and its influencing factors. The main questions it aims to answer are:
Is corneal incision healing worse in diabetic patients after cataract surgery than in non-diabetic patients? What are the factors affecting corneal incision healing after cataract surgery in diabetic patients?
The results of anterior segment optical coherence tomography before and after cataract surgery in cataract patients with or without diabetes will be collected and analyzed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Diabetes group | |||
| Control group |
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| Measure | Description | Time Frame |
|---|---|---|
| volume of half cornea with surgical incision | Before surgery; 1 week after surgery; 1 month after surgery | |
| Defect of corneal incision healing | Opening of internal orifice; Endothelial dislocation; Descemet's membrane detachment | 1 week after surgery; 1 month after surgery |
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Inclusion Criteria:
Patients who experience blurred vision and painless visual acuity decline, and are diagnosed with cataract (with or without diabetes) through reliable intraocular pressure, visual acuity and slit lamp examinations, and for whom phacoemulsification of cataract can be considered.
Exclusion Criteria:
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Patients who were initially diagnosed with cataract and treated with phacoemulsification and intraocular lens implantation at Zhongnan Hospital of Wuhan University from April 1, 2024 to December 31, 2024.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zhongnan Hospital of Wuhan University | Wuhan | Hubei | 430071 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 42312563 | Derived | Chen Y, Fu Y, Li L, Li W, Zhang Y, Liu Y, Zhang Q, Ke M. OCT-Based Quantitative Comparison of Full-Thickness Healing of Corneal Incisions in Cataract Surgery Between Diabetic and Nondiabetic Patients. Cornea. 2026 Jun 19. doi: 10.1097/ICO.0000000000004216. Online ahead of print. |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D002386 | Cataract |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| D007905 | Lens Diseases |
| D005128 | Eye Diseases |