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This study aims to compare the effects of external oblique intercostal block versus paravertebral block on postoperative pain and complications in patients undergoing open nephrectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Paravertebral block | Active Comparator | Patients scheduled to undergo thoracic paravertebral block will receive an injection of 20 ml of 0.25% bupivacaine hydrochloride into the paravertebral space between the parietal pleura and the costotransverse ligament using a block needle under ultrasound guidance. |
|
| External Oblique Intercostal Block | Active Comparator | Patients scheduled to undergo an external oblique intercostal block will receive an injection of 30 ml of 0.25% bupivacaine hydrochloride between the external oblique muscle and the intercostal muscle at the level of the 6th rib, using a block needle under ultrasound guidance. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bupivacaine | Drug | Used for regional anesthesia during nephrectomy procedure (e.g., paravertebral or external oblique intercostal block) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative Pain Score | Pain intensity measured using Visual Analog Scale at rest. (Visual Analog Scale ranging from 0 = no pain to 10 = worst pain imaginable; higher scores indicate worse pain). | Up to 24 hours after surgery |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hacettepe University Faculty of Medicine Hospital | Ankara | Turkey (Türkiye) |
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| morphine | Drug | Used for postoperative pain control via PCA device |
|
| paracetamol | Drug | Used as part of postoperative multimodal analgesia |
|
| Diclofenac | Drug | Used as part of postoperative multimodal analgesia |
|
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| D009020 | Morphine |
| D000082 | Acetaminophen |
| D004008 | Diclofenac |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
| D000588 | Amines |
| D009022 | Morphine Derivatives |
| D009019 | Morphinans |
| D053610 | Opiate Alkaloids |
| D000470 | Alkaloids |
| D006571 | Heterocyclic Compounds |
| D006572 | Heterocyclic Compounds, Bridged-Ring |
| D006576 | Heterocyclic Compounds, 4 or More Rings |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D010616 | Phenanthrenes |
| D011084 | Polycyclic Aromatic Hydrocarbons |
| D011083 | Polycyclic Compounds |
| D000083 | Acetanilides |
| D010648 | Phenylacetates |
| D000146 | Acids, Carbocyclic |
| D002264 | Carboxylic Acids |
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