The Effect of Heat Exposure on Physiological Markers

The Effect of Exertional and Exogenous Heating on Physiological Markers

This study is the first to examine the effects of core temperature elevation on kynurenine pathway (KP) metabolites in healthy young males. It was hypothesized that rise in core temperature due to both pasive heating and exercise will initiate a stress response, affecting the concentration of KP metabolites. Additionally, it was expected that the exercise would produce more pronounced effects due to the increased cardiovascular, mechanical, and metabolic demands associated with it. Thus, the the main purpose of the present study was to investigate and to compare the effects of two distinct heat stress modalities on KP metabolites.

Inclusion Criteria:

• healthy adults;
• age between 18 - 36 years;
• physically active (exercising 2-3 times per week);
• non-smoking.

Exclusion Criteria:

• a body mass index (BMI) > 30 kg/m2;
• neurological, cardiovascular, metabolic, and/or inflammatory diseases, or conditions that could be worsened by exposure to interventions and that could affect experimental variables;
• involvement in temperature manipulation program for ≥ 3 months.