The investigator aims to prospectively enroll patients who were referred for transthorcic echocardiography (TTE) for the assessment of stable chest pain (SCP) suspected of obstructive coronary artery disease (CAD). All patients underwent TTE according to established guidelines and local institutional protocols. This study will determine if TTE-based imaging evaluation can provide more informaton to improve clinical management for SCP, including fewer MACE and better decision-making of downstream investigations and therapeutic interventions.

Inclusion Criteria:

• symptomatic patients with SCP suspected of obstructive CAD.
• referred for TTE for the assessment of SCP.
• ≥18 years of age.
• signed informed consent.

Exclusion Criteria:

• acute coronary syndromes
• previous CAD or coronary revascularization
• nonsinus rhythm
• cardiomyopathy, valvular disease, congenital heart disease or left cardiac insufficiency because of other reasons

Patients who were referred for TTE for the assessment of SCP suspected of CAD.