A Phase 3, Multi-Center, Randomized, Open-Label Clinical Study of Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy as First-Line Treatment in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
A Phase 3, Multi-Center, Randomized, Open-Label Clinical Study of Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy as First-Line Treatment in Patients With Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma
This study is designed to assess the levels of drug exposure following treatment with tislelizumab administered as a subcutaneous (SC) injection compared to intravenous infusion (IV) as first-line therapy in adults with gastric or gastroesophageal junction (GEJ) that is locally advanced and cannot be surgically removed or has spread from the stomach to other areas of the body. Approximately 351 patients will be participating in this study. The study is composed of a screening period, a treatment period, and a follow-up period.
Our company, previously known as BeiGene, is now officially BeOne Medicines. Because some of our older studies were sponsored under the name BeiGene, you may see both names used for this study on this website.
Inclusion Criteria:
Exclusion Criteria:
NOTE: Other protocol defined Inclusion/Exclusion criteria may apply.
clinicaltrials@beonemed.com1-877-828-5568
Chandler, Arizona 85224-5665, United States
Colorado Springs, Colorado 80909, United States
Kansas City, Kansas 66160-8500, United States
Caba, 1425, Argentina
Ciudad Autonoma Buenos Aires, 1426, Argentina
São José do Rio Preto, 15090-000, Brazil
São Paulo, 01246-000, Brazil
Beijing, Beijing Municipality 100021, China
Nanjing, Jiangsu 210008, China
Ganzhou, Jiangxi 341000, China
Tianjin, Tianjin Municipality 300060, China
Wenzhou, Zhejiang 325000, China
Kitakyushu, Fukuoka 806-0034, Japan
SakaiShi, Osaka 591-8025, Japan
Takatsukishi, Osaka 569-8686, Japan
Kitaadachigun, Saitama 362-0806, Japan
Hamamatsushi, Shizuoka 431-3192, Japan
Bunkyoku, Tokyo 113-8519, Japan
SumidaKu, Tokyo 130-8575, Japan
Seongnam-si, Gyeonggi-do 13620, South Korea
BukGu, Gyeongsangbukdo 41404, South Korea
GangnamGu, Seoul Teugbyeolsi 06351, South Korea
SeodaemunGu, Seoul Teugbyeolsi 03722, South Korea
SongpaGu, Seoul Teugbyeolsi 05505, South Korea
Ankara, 06200, Turkey (Türkiye)