A Randomized, Placebo-Controlled, Double-Blind Phase 3 Study to Evaluate the Efficacy and Safety of Tislelizumab (BGB-A317) in Combination With Chemotherapy as First-Line Treatment in Patients With Unresectable, Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
A Randomized, Placebo-Controlled, Double-Blind Phase 3 Study to Evaluate the Efficacy and Safety of Tislelizumab (BGB-A317) in Combination With Chemotherapy as First-Line Treatment in Patients With Unresectable, Locally Advanced Recurrent or Metastatic Esophageal Squamous Cell Carcinoma
The purpose of this study is to evaluate the efficacy and safety of tislelizumab as first line treatment in combination with chemotherapy in participants with advanced unresectable/metastatic esophageal squamous cell carcinoma (ESCC).
Key Inclusion Criteria:
Key Exclusion Criteria:
NOTE: Other protocol defined Inclusion/Exclusion criteria may apply.
Hefei, Anhui 230088, China
Guangzhou, Guangdong 510405, China
Wuxi, Jiangsu 214062, China
Hangzhou, Zhejiang 310003, China
LevalloisPerret, 92300, France
SaintHerblain, 44805, France
Heilbronn, 74078, Germany
Akitashi, Akita 010-8543, Japan
Fukuokacity, Fukuoka 810-8563, Japan
AkashiShi, Hyōgo 673-0021, Japan
Amagasakishi, Hyōgo 660-8511, Japan
KyotoShi, Kyoto 602-8566, Japan
OsakaShi, Osaka 541-8567, Japan
Suitashi, Osaka 565-0871, Japan
Kitaadachigun, Saitama 362-0806, Japan
ChuoKu, Tokyo 104-0045, Japan
Warsaw, 02-781, Poland
ClujNapoca, 400015, Romania
ClujNapoca, 400641, Romania
ClujNapoca, 407280, Romania
Arkhangelsk, Arkhangelskaya oblast 163045, Russia
Kuzmolovsky, Leningradskaya Oblast' 188663, Russia
RostovonDon, Rostov Oblast 344022, Russia
SaintPetersburg, Sankt-Peterburg 197022, Russia
SaintPetersburg, 197758, Russia
Dalseogu, Daegu Gwang'yeogsi 42601, South Korea
BundangGu SeongnamSi, Gyeonggi-do 13496, South Korea
BundangGu SeongnamSi, Gyeonggi-do 13620, South Korea
NamdongGu, Incheon Gwang'yeogsi 21565, South Korea
HwasunGun, Jeollanam-do 58128, South Korea
DongjakGu, Seoul Teugbyeolsi 07061, South Korea
GuroGu, Seoul Teugbyeolsi 08308, South Korea
SeochoGu, Seoul Teugbyeolsi 06591, South Korea
SongpaGu, Seoul Teugbyeolsi 05505, South Korea
Liuying Dist, 73657, Taiwan
North Dist, 404327, Taiwan
Yongkang Dist, 710, Taiwan
Greater Manchester, M20 4BX, United Kingdom